Activity of telavancin compared to other agents against coagulase-negative staphylococci with different resistotypes by time kill

被引：7
作者：
Lin, Gengrong [1 ]
Pankuch, Glenn A. [1 ]
Appelbaum, Peter C. [1 ]
Kosowska-Shick, Klaudia [1 ]
机构：
[1] Milton S Hershey Med Ctr, Hershey, PA 17033 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2012年 / 73卷 / 03期
关键词：
Telavancin; Staphylococcus aureus; Time kill; IN-VITRO ACTIVITY; VANCOMYCIN; LIPOGLYCOPEPTIDE; SURVEILLANCE; TEICOPLANIN;
D O I：
10.1016/j.diagmicrobio.2012.04.003
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4x MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By contrast, linezolid was mainly bacteriostatic and teicoplanin was bactericidal to 7 strains tested at 4x MIC after 24 h. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码：287 / 289
页数：3
相关论文
共 18 条
[1]  
[Anonymous], 2009, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically
[2]  
Approved Standard, VEighth
[3]  
[Anonymous], 2010, CLSI Document M100-S20
[4]   Decreased Susceptibility to Teicoplanin and Vancomycin in Coagulase-Negative Staphylococci Isolated from Orthopedic-Device-Associated Infections [J].
Cremniter, Julie ;
Slassi, Asma ;
Quincampoix, Jean-Charles ;
Sivadon-Tardy, Valerie ;
Bauer, Thomas ;
Porcher, Raphael ;
Lortat-Jacob, Alain ;
Piriou, Philippe ;
Judet, Thierry ;
Herrmann, Jean-Louis ;
Gaillard, Jean-Louis ;
Rottman, Martin .
JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (04) :1428-1431
[5]   Five-test simple scheme for species-level identification of clinically significant coagulase-negative staphylococci [J].
De Paulis, AN ;
Predari, SC ;
Chazarreta, CD ;
Santoianni, JE .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (03) :1219-1224
[6]   In vitro activity of telavancin against recent Gram-positive clinical isolates:: results of the 2004-05 Prospective European Surveillance Initiative [J].
Draghi, Deborah C. ;
Benton, Bret M. ;
Krause, Kevin M. ;
Thornsberry, Clyde ;
Pillar, Chris ;
Sahm, Daniel F. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 62 (01) :116-121
[7]   Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States [J].
Draghi, Deborah C. ;
Benton, Bret M. ;
Krause, Kevin M. ;
Thornsberry, Clyde ;
Pillar, Chris ;
Sahm, Daniel F. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (07) :2383-2388
[8]   Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus [J].
Higgins, DL ;
Chang, R ;
Debabov, DV ;
Leung, J ;
Wu, T ;
Krause, KA ;
Sandvik, E ;
Hubbard, JM ;
Kaniga, K ;
Schmidt, DE ;
Gao, QF ;
Cass, RT ;
Karr, DE ;
Benton, BM ;
Humphrey, PP .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (03) :1127-1134
[9]   Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis [J].
Julian, Kathleen ;
Kosowska-Shick, Klaudia ;
Whitener, Cynthia ;
Roos, Martin ;
Labischinski, Harald ;
Rubio, Aileen ;
Parent, Leslie ;
Ednie, Lois ;
Koeth, Laura ;
Bogdanovich, Tatiana ;
Appelbaum, Peter C. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (09) :3445-3448
[10]   Molecular and epidemiologic characteristics of linezolid-resistant coagulase-negative staphylococci at a tertiary care hospital [J].
Kosowska-Shick, Klaudia ;
Julian, Kathleen G. ;
McGhee, Pamela L. ;
Appelbaum, Peter C. ;
Whitener, Cynthia J. .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2010, 68 (01) :34-39
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