Effect of the RNase from Bacillus intermedius on the Trophic Organization of the Mitotic cycle of Candida utilis

The effect of the RNase from Bacillus intermedius on the growth and trophic cycle of Candida utilis was studied. RNase at concentrations of 0.001-0.01 mu g/ml stimulated yeast growth by 30-40% as compared to the control, reduced the mitotic cycle of the yeast by shortening its G1 phase, and decreased the number of exotrophic cells in the G1 phase to a minimum. It is suggested that RNase is involved in the regulation of the transition of cells from the exo- to endotrophic state.