Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease

被引：89

作者：

Saeki, Takako ^{[1
]}

Saito, Akihiko ^{[2
]}

Hiura, Tohru ^{[3
,4
]}

Yamazaki, Hajime ^{[1
]}

Emura, Iwao ^{[5
]}

Ueno, Mitsuhiro ^{[3
,4
]}

Miyamura, Syoji ^{[1
]}

Gejyo, Fumitake ^{[3
,4
]}

机构：

[1] Nagaoka Red Cross Hosp, Dept Internal Med, Nagaoka, Niigata 9402085, Japan

[2] Niigata Univ, Grad Sch Med & Dent Sci, Dept Appl Mol Med, Niigata, Japan

[3] Niigata Univ, Grad Sch Med & Dent Sci, Div Clin Nephrol, Niigata, Japan

[4] Niigata Univ, Grad Sch Med & Dent Sci, Div Rheumatol, Niigata, Japan

[5] Nagaoka Red Cross Hosp, Dept Pathol, Nagaoka, Niigata 9402085, Japan

来源：

INTERNAL MEDICINE | 2006年 / 45卷 / 03期

关键词：

IgG4; autoimmune pancreatitis; Sjogren's syndrome; Mikulicz's disease; tubulointerstitial nephritis;

D O I：

10.2169/internalmedicine.45.1431

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune pancreatitis, but also with other systemic lymphoplasmacytic disease.

引用

页码：163 / 167

页数：5

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