Beneficial effects of the n-3 long-chain polyunsaturated fatty acids in surgical patients: Updating the evidence

被引：7
作者：
Bernabe-Garcia, M. [1 ]
Lopez-Alarcon, M. [1 ]
Blanco-Favela, F. [2 ]
Mancilla-Ramirez, J. [3 ]
Mansilla-Olivares, A. [4 ]
Arredondo-Garcia, J. L. [5 ]
机构：
[1] Hosp Pediat Mexico City, Ctr Med Nacl Siglo 21, Inst Mexicano Seguro Social, Unidad Invest Med Nutr, Mexico City, DF, Mexico
[2] Hosp Pediat Mexico City, Ctr Med Nacl Siglo 21, Inst Mexicano Seguro Social, Unidad Invest Med Inmunol, Mexico City, DF, Mexico
[3] Inst Nacl Perinatol, Mexico City, DF, Mexico
[4] Hosp Cardiol, Ctr Med Nacl Siglo 21, IMSS, Unidad Invest Biomol, Mexico City, DF, Mexico
[5] Inst Nacl Pediat, Unidad Apoyo Invest Clin, Mexico City, DF, Mexico
来源：
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 2011年 / 85卷 / 05期
关键词：
Fish oil; n-3 fatty acids; DHA and EPA; Surgery; Surgical; Postoperative; Clinical outcome; TOTAL PARENTERAL-NUTRITION; FISH-OIL; LIPID EMULSIONS; OMEGA-3-FATTY-ACIDS IMPROVE; LEUKOTRIENE SYNTHESIS; CRITICAL ILLNESS; INFLAMMATION; MECHANISMS; SURGERY; SEPSIS;
D O I：
10.1016/j.plefa.2011.04.012
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The use of n-3 polyunsaturated fatty acids in surgical patients has risen by the fact that this may attenuate systemic and acute inflammatory responses secondary to surgical trauma through modulation of inflammatory mediators and cell membrane interactions. Moreover, the inclusion of n-3 fatty acids in clinical trials as part of the therapy in patients, who expect to undergo a surgical stress, suggests benefits on clinical progress. Therefore, the objective of this article is to review data from n-3 polyunsaturated fatty acid effects on biochemical parameters and on reduced length of hospitalization, number of infections, and mortality as main clinical outcomes in human surgical patients. (C) 2011 Elsevier Ltd. All rights reserved.
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收藏
页码：261 / 266
页数：6
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