Ventricular fibrillation in a swine model of acute pediatric asphyxial cardiac arrest

被引：18
作者：
Berg, RA
Kern, KB
Otto, CW
Samson, RA
Sanders, AB
Ewy, GA
机构：
[1] Dept. of Pediat. and Steel Mem. C., University Heart Center, Univ. of Arizona Coll. of Medicine, Tucson, AZ 85724-5073
[2] Department of Medicine, University Heart Center, Univ. of Arizona Coll. of Medicine, Tucson, AZ 85724-5037
[3] Depts. of Anesth. and Medicine, University Heart Center, Univ. of Arizona Coll. of Medicine, Tucson, AZ 85724-5114
[4] Section of Cardiology/3302, University Heart Center, Univ. of Arizona Coll. of Medicine, Tucson, AZ 85724-5073
[5] Department of Surgery, University Heart Center, Univ. of Arizona Coll. of Medicine, Tucson, AZ 85724-5057
来源：
RESUSCITATION | 1996年 / 33卷 / 02期
关键词：
cardiac arrest; ventricular fibrillation; pediatric; asphyxia; hypoxia; hypercarbia;
D O I：
10.1016/S0300-9572(96)01013-1
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Study objective: To determine cardiac rhythms in a swine model of acute pediatric asphyxial cardiac arrest. Design: Prospective electrocardiographic evaluation of 36 piglets. Setting: University hospital laboratory. Intervention: Piglets were acutely asphyxiated by endotracheal tube clamping until 10 min after loss of aortic pulsations. Resuscitative efforts were then provided. Results: None of the animals had ventricular fibrillation (VF) when loss of aortic pulsations occurred (11+/-2 min after clamping). Fourteen of the 36 piglets exhibited VF during the asphyxial insult. VF converted to asystole in four piglets prior to resuscitation. Immediately prior to resuscitation, VF occurred in 10 piglets, asystole in 19 piglets, and bradyarrhythmias in seven piglets. Conclusion: VF occurs frequently in this piglet model of prolonged asphyxial cardiac arrest, consistent with recent observations in pediatric prehospital cardiac arrests. VF occurred late in the asphyxial process. Copyright (C) 1996 Elsevier Science Ireland Ltd
引用
收藏
页码：147 / 153
页数：7
相关论文
共 52 条
123456