Pollution by metals: Is there a relationship in glycemic control?

被引：34

作者：

Gonzalez-Villalva, Adriana ^{[1
]}

Colin-Barenque, Laura ^{[2
]}

Bizarro-Nevares, Patricia ^{[1
]}

Rojas-Lemus, Marcela ^{[1
]}

Rodriguez-Lara, Vianey ^{[1
]}

Garcia-Pelaez, Isabel ^{[1
]}

Ustarroz-Cano, Martha ^{[1
]}

Lopez-Valdez, Nelly ^{[1
]}

Carlos Albarran-Alonso, Juan ^{[1
]}

Fortoul, Teresa I. ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Fac Med, Dept Biol Celular & Tisular, Mexico City 04510, DF, Mexico

[2] Univ Nacl Autonoma Mexico, FES Iztacala, Lab Neuromorfol, Mexico City 54090, Edo De Mexico, Mexico

来源：

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2016年 / 46卷

关键词：

Metals; Pollution; Hyperglycemia; Hypoglycemia; Diabetes; Insulin; TYPE-2; DIABETES-MELLITUS; INSULIN-RESISTANCE; AIR-POLLUTION; EXPOSURE; SUPPLEMENTATION; METABOLISM; GLUCOSE; NICKEL; RISK; RATS;

D O I：

10.1016/j.etap.2016.06.023

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

There are evidences of environmental pollution and health effects. Metals are pollutants implicated in systemic toxicity. One of the least studied effects, but which is currently becoming more important, is the effect of metals on glycemic control. Metals have been implicated as causes of chronic inflammation and oxidative stress and are associated to obesity, hyperglycemia and even diabetes. Arsenic, iron, mercury, lead, cadmium and nickel have been studied as a risk factor for hyperglycemia and diabetes. There is another group of metals that causes hypoglycemia such as vanadium, chromium, zinc and magnesium by different mechanisms. Zinc, magnesium and chromium deficiency is associated with increased risk of diabetes. This review summarizes some metals involved in glycemic control and pretends to alert health professionals about considering environmental metals as an important factor that could explain the poor glycemic control in patients. Further studies are needed to understand this poorly assessed problem. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：337 / 343

页数：7

共 44 条

[1] Toxicity of cadmium and protective effect of bee honey, vitamins C and B complex [J].