Ifosfamide combined with toremifene in the treatment of non-small cell lung cancer

被引：2
|
作者：
Salomaa, ER [1 ]
Liippo, K [1 ]
Ellmen, J [1 ]
Komi, J [1 ]
机构：
[1] ORION CORP FARMOS,FIN-20101 TURKU,FINLAND
来源：
LUNG CANCER | 1996年 / 16卷 / 01期
关键词：
non-small cell lung cancer; chemotherapy; multi-drug resistance; toremifene; ifosfamide;
D O I：
10.1016/S0169-5002(96)00613-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The efficacy and safety of toremifene-ifosfamide as a first-line chemotherapy in non-small cell lung cancer were assessed. Sixteen patients were treated with oral toremifene (420 mg on days 1-4 and 240 mg on day 5) followed by ifosfamide infusion 5 g/m(2) on day 5 every 3 weeks 1-6 times. Toremifene at the doses used did not enhance the effect or toxicity of ifosfamide in previously untreated non-small cell lung cancer patients. Copyright (C) 1996 Elsevier Science Ireland Ltd.
引用
收藏
页码：75 / 80
页数：6
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