Microwave-assisted neat synthesis of -aminophosphonate/phosphinate derivatives of 2-(2-aminophenyl)benzothiazole as potent antimicrobial and antioxidant agents

被引：25

作者：

Basha, Shaik Thaslim ^{[1
]}

Sudhamani, Hasti ^{[1
]}

Rasheed, Syed ^{[1
]}

Venkateswarlu, Nagam ^{[2
]}

Vijaya, Tartte ^{[2
]}

Raju, Chamarthi Naga ^{[1
]}

机构：

[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India

[2] Sri Venkateswara Univ, Dept Bot, Tirupati, Andhra Pradesh, India

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2016年 / 191卷 / 10期

关键词：

2-(2-Aminophenyl) benzothiazole; neat conditions; microwave irradiation; Kabachnik-Fields reaction; antimicrobial and antioxidant activity; ALPHA-AMINOPHOSPHONATES; SOLVENT; INHIBITORS; CYTOTOXICITY; ACID;

D O I：

10.1080/10426507.2016.1192629

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of diethyl/ethylphenyl {2-(benzo[d]thiazol-2-yl)phenylamino}phosphonates and phosphinates were synthesized under microwave irradiation and neat conditions via Kabachnik-Fields reaction in high yields (80%-93%). The compounds were screened for antimicrobial and antioxidant properties. A few compounds showed effective antibacterial and antifungal activities at MIC value 12.5g/mL as compared with the standard at MIC value 6.25g/mL. [GRAPHICS] .

引用

页码：1339 / 1343

页数：5

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