Starting from the influence of financial crisis on American economy, this paper has analyzed the background of the implementation of "re-industrialization" strategy in the USA, analyzed the connotation of the "re-industrialization" strategy of the USA, and its influence on Chinese enterprises. According to this paper, the America's "re-industrialization" USA will have impact on the development of Chinese enterprises. In, order to make preparations in advance, Chinese enterprises should take it seriously and strategically. This paper has brought forward coping methods to "re-industrialization" strategy of the USA, that is, firstly, amalgamate and restructure enterprises to make them stronger and bigger; secondly, improve the core competitiveness through science and technology innovation; thirdly, augment the market share through brand innovation; fourthly, improve the cohesion of enterprise through organization innovation; fifthly, improve the quality of human resources through training.