Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

被引：66
作者：
Joosten, Simone A. [1 ]
Sullivan, Lucy C. [2 ]
Ottenhoff, Tom H. M. [1 ]
机构：
[1] Leiden Univ, Dept Infect Dis, Med Ctr, NL-2333 ZA Leiden, Netherlands
[2] Univ Melbourne, Dept Microbiol & Immunol, Peter Doherty Inst Infect & Immun, Melbourne, Vic 3010, Australia
来源：
JOURNAL OF IMMUNOLOGY RESEARCH | 2016年 / 2016卷
关键词：
PEPTIDE-BINDING-SPECIFICITY; HUMAN CYTOMEGALOVIRUS; E EXPRESSION; E GENE; ANTIGEN; RECOGNITION; IDENTIFICATION; LYMPHOCYTES; SUBSET; TUBERCULOSIS;
D O I：
10.1155/2016/2695396
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human HLA-E can, in addition to self-antigens, also present pathogen-derived sequences, which elicit specific T-cell responses. T-cells recognize their antigen presented by HLA-E highly specifically and have unique functional and phenotypical properties. Pathogen specific HLA-E restricted CD8(+) T-cells are an interesting new player in the field of immunology. Future work should address their exact roles and relative contributions in the immune response against infectious diseases.
引用
收藏
页数：11
相关论文
共 71 条
[1]   IDENTIFICATION OF A TAP-DEPENDENT LEADER PEPTIDE RECOGNIZED BY ALLOREACTIVE T-CELLS SPECIFIC FOR A CLASS IB ANTIGEN [J].
ALDRICH, CJ ;
DECLOUX, A ;
WOODS, AS ;
COTTER, RJ ;
SOLOSKI, MJ ;
FORMAN, J .
CELL, 1994, 79 (04) :649-658
[2]   HLA-E-Restricted Cross-Recognition of Allogeneic Endothelial Cells by CMV-Associated CD8 T Cells: A Potential Risk Factor following Transplantation [J].
Allard, Mathilde ;
Tonnerre, Pierre ;
Nedellec, Steven ;
Oger, Romain ;
Morice, Alexis ;
Guilloux, Yannick ;
Houssaint, Elisabeth ;
Charreau, Beatrice ;
Gervois, Nadine .
PLOS ONE, 2012, 7 (11)
[3]  
Anthony Nolan Research Institute, 2009, HLA CLASS 1 2 SEQ AL
[4]   Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies [J].
Apps, Richard ;
Murphy, Shawn P. ;
Fernando, Raymond ;
Gardner, Lucy ;
Ahad, Tashmeeta ;
Moffett, Ashley .
IMMUNOLOGY, 2009, 127 (01) :26-39
[5]   The Dendritic Cell Synapse: A Life Dedicated to T Cell Activation [J].
Benvenuti, Federica .
FRONTIERS IN IMMUNOLOGY, 2016, 7
[6]  
Bouwer HGA, 1997, J IMMUNOL, V159, P2795
[7]   The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9 [J].
Braud, V ;
Jones, EY ;
McMichael, A .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1997, 27 (05) :1164-1169
[8]   HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C [J].
Braud, VM ;
Allan, DSJ ;
O'Callaghan, CA ;
Söderström, K ;
D'Andrea, A ;
Ogg, GS ;
Lazetic, S ;
Young, NT ;
Bell, JI ;
Phillips, JH ;
Lanier, LL ;
McMichael, AJ .
NATURE, 1998, 391 (6669) :795-799
[9]   Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines (vol 49, 971, 2019) [J].
Caccamo, Nadia ;
Pietra, Gabriella ;
Sullivan, Lucy C. ;
Brooks, Andrew G. ;
Prezzemolo, Teresa ;
La Manna, Marco P. ;
Di Liberto, Diana ;
Joosten, Simone A. ;
van Meijgaarden, Krista E. ;
Di Carlo, Paola ;
Titone, Lucina ;
Moretta, Lorenzo ;
Mingari, Maria C. ;
Ottenhoff, Tom H. M. ;
Dieli, Francesco .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2022,
[10]   The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch [J].
Celik, Alexander A. ;
Kraemer, Thomas ;
Huyton, Trevor ;
Blasczyk, Rainer ;
Bade-Doeding, Christina .
IMMUNOGENETICS, 2016, 68 (01) :29-41
12345678