Brain contrast-enhanced ultrasonography and elastography in infants

被引:5
作者
Hwang, Misun [1 ]
Zhang, Zeng [2 ]
Katz, Joseph [2 ]
Freeman, Colbey [3 ]
Kilbaugh, Todd [4 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Dept Radiol, Philadelphia, PA USA
[2] Johns Hopkins Univ, Dept Mech Engn, Baltimore, MD USA
[3] Univ Penn, Perelman Sch Med, Dept Radiol, Philadelphia, PA USA
[4] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Dept Anesthesiol & Crit Care Med, Philadelphia, PA USA
关键词
Contrast-enhanced ultrasound; Elastography; Infants; Brain; MAGNETIC-RESONANCE ELASTOGRAPHY; HYPOXIC-ISCHEMIC INJURY; NEONATAL BRAIN; IN-VIVO; ULTRASOUND; STIFFNESS; PERFUSION; PRESSURE; HYDROCEPHALUS; SONOGRAPHY;
D O I
10.14366/usg.21224
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Advanced ultrasound techniques, including brain contrast- enhanced ultrasonography and elastography, are increasingly being explored to better understand infant brain health. While conventional brain ultrasonography provides a convenient, noninvasive means of assessing major intracranial pathologies, its value in revealing functional and physiologic insights into the brain lags behind advanced imaging techniques such as magnetic resonance imaging. In this regard, contrast-enhanced ultrasonography provides highly precise functional information on macrovascular and microvascular perfusion, while brain elastography offers information on brain stiffness that may be associated with relevant physiological factors of diagnostic, therapeutic, and/or prognostic utility. This review details the technical background, current understanding and utility, and future directions of these two emerging advanced ultrasound techniques for neonatal brain applications.
引用
收藏
页码:633 / 649
页数:17
相关论文
共 75 条
  • [61] Contrast-Enhanced Ultrasonography During Extracorporeal Membrane Oxygenation
    Squires, Judy H.
    Alcamo, Alicia M.
    Horvat, Christopher
    Sharma, Mahesh S.
    [J]. JOURNAL OF ULTRASOUND IN MEDICINE, 2019, 38 (02) : 545 - 548
  • [62] The Wash-Out of Contrast-Enhanced Ultrasound for Evaluation of Hypoxic Ischemic Injury in Neonates and Infants
    Sridharan, Anush
    Riggs, Becky
    Darge, Kassa
    Huisman, Thierry A. G. M.
    Hwang, Misun
    [J]. ULTRASOUND QUARTERLY, 2022, 38 (01) : 36 - 42
  • [63] In vivo viscoelastic properties of the brain in normal pressure hydrocephalus
    Streitberger, Kaspar-Josche
    Wiener, Edzard
    Hoffmann, Jan
    Freimann, Florian Baptist
    Klatt, Dieter
    Braun, Juergen
    Lin, Kui
    McLaughlin, Joyce
    Sprung, Christian
    Klingebiel, Randolf
    Sack, Ingolf
    [J]. NMR IN BIOMEDICINE, 2011, 24 (04) : 385 - 392
  • [64] Su Y, 2015, CLIN EXP OBSTET GYN, V42, P797
  • [65] Wang SD, 2015, INT J CLIN EXP PATHO, V8, P12177
  • [66] Brain stiffness increases with myelin content
    Weickenmeier, J.
    de Rooij, R.
    Budday, S.
    Steinmann, P.
    Ovaert, T. C.
    Kuhl, E.
    [J]. ACTA BIOMATERIALIA, 2016, 42 : 265 - 272
  • [67] Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia
    Wintermark, P.
    Hansen, A.
    Gregas, M. C.
    Soul, J.
    Labrecque, M.
    Robertson, R. L.
    Warfield, S. K.
    [J]. AMERICAN JOURNAL OF NEURORADIOLOGY, 2011, 32 (11) : 2023 - 2029
  • [68] Perfusion-weighted magnetic resonance imaging patterns of hypoxic-ischemic encephalopathy in term neonates
    Wintermark, Pia
    Moessinger, Adrien C.
    Gudinchet, Francois
    Meuli, Reto
    [J]. JOURNAL OF MAGNETIC RESONANCE IMAGING, 2008, 28 (04) : 1019 - 1025
  • [69] Evidence of Changes in Brain Tissue Stiffness After Ischemic Stroke Derived From Ultrasound-Based Elastography
    Xu, Zinnia S.
    Lee, Rona J.
    Chu, Stephanie S.
    Yao, Anning
    Paun, Marla K.
    Murphy, Sean P.
    Mourad, Pierre D.
    [J]. JOURNAL OF ULTRASOUND IN MEDICINE, 2013, 32 (03) : 485 - 494
  • [70] Hydrocephalus Decreases Arterial Spin-Labeled Cerebral Perfusion
    Yeom, K. W.
    Lober, R. M.
    Alexander, A.
    Cheshier, S. H.
    Edwards, M. S. B.
    [J]. AMERICAN JOURNAL OF NEURORADIOLOGY, 2014, 35 (07) : 1433 - 1439