Successively Recycle Waste as Catalyst: A One-Pot Wittig/1,4-Reduction/Paal-Knorr Sequence for Modular Synthesis of Substituted Furans

被引：65
作者：
Chen, Long [1 ]
Du, Yi [2 ]
Zeng, Xing-Ping [1 ]
Shi, Tao-Da [1 ]
Zhou, Feng [1 ]
Zhou, Jian [1 ,3 ]
机构：
[1] E China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Shanghai 200092, Peoples R China
[3] Shanghai Inst Organ Chem, CAS, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2015年 / 17卷 / 06期
关键词：
PHOSPHINE-INITIATED REACTIONS; PAAL-KNORR REACTION; BETA-AMINO ESTERS; O BOND FORMATION; POLYSUBSTITUTED FURANS; TETRASUBSTITUTED FURANS; ENANTIOSELECTIVE SYNTHESIS; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; (2-FURYL)CARBENE COMPLEXES;
D O I：
10.1021/acs.orglett.5b00442
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot tandem Wittig/conjugate reduction/PaalKnorr reaction is reported for the synthesis of di- or trisubstituted furans. This novel sequence first demonstrates the possibility of successively recycling waste from upstream steps to catalyze downstream reactions.
引用
收藏
页码：1557 / 1560
页数：4
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