Association of Sleep Duration and Blood Pressure in Adolescents: A Multicenter Study

BACKGROUND Evidence suggests that sleep duration is related to blood pressure (BP), but the findings are still inconsistent for adolescents. OBJECTIVE To analyze the association between sleep duration and BP in Brazilian adolescents between 12 and 17 years of age. METHODS This study is part of the Study of Cardiovascular Risk in Adolescents (ERICA), a multicenter, school-based, cross-sectional study in 273 municipalities in Brazil. The sample consisted of 65,643 adolescents. Sleep duration was measured by a subjective method, and BP was measured by the oscillometric method. Multiple linear regression analyses were performed to evaluate the association between sleep duration and BP. RESULTS The mean sleep duration was 8.14 hours (+/- 1.40), with significant difference between the groups according to BP levels (P < 0.0001). The mean systolic and diastolic BP were 110.59 (+/- 11.87) and 65.85 (+/- 7.94) mm Hg, respectively, in the group of adolescents. Sleep duration was significantly associated with BR Each increase 1 hour in sleep was associated with BP reduction in both sexes combined (P < 0.0001). Considering the effects of covariates, each increase 1 hour in sleep was associated with systolic BP (SBP) reduction among boys (P = 0.004) and SBP elevation among girls (P = 0.009), after full adjustment. CONCLUSION The results suggest that each increase in sleep duration was associated with SBP elevation among girls. Such findings may have important implications for cardiovascular health in adolescence.