Biocompatible superparamagnetic iron oxide nanoparticles used for contrast agents: a structural and magnetic study

被引：84

作者：

Gamarra, LF

Brito, GES

Pontuschka, WM

Amaro, E

Parma, AHC

Goya, GF

机构：

[1] Univ Sao Paulo, Inst Phys, BR-05315970 Sao Paulo, Brazil

[2] USP, Inst Radiol InRad, Fac Med, BR-05403001 Sao Paulo, Brazil

[3] Hosp Israel Albert Einstein, IEP, BR-05651901 Sao Paulo, Brazil

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 289卷

关键词：

magnetic nanoparticles; contrast media; magnetic anisotropy;

D O I：

10.1016/j.jmmm.2004.11.123

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The magnetic properties of different biocompatible magnetic iron oxide nanoparticles (MION) are presented. Dextran-coated, magnetite (Fe3O4) MIONs were studied as supplied and after lyophilization, to disentangle the effects of particle interactions. All samples showed superparamagnetic behavior at room temperature, with blocking transitions at T-B similar to 40-56 K (at 100 Oe), depending on the particle interactions. The dynamics of the thermally activated blocking process reveals that the effect of dipolar interactions is to increase the energy barriers of the individual particles. (c) 2004 Elsevier B.V. All rights reserved.

引用

页码：439 / 441

页数：3

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