Localization of transferrin binding protein in relation to iron, ferritin, and transferrin receptors in the chicken cerebellum

被引：14

作者：

Cho, SS

Shin, DH

Lee, KH

Hwang, DH

Chang, KY

机构：

[1] Seoul Natl Univ, Coll Med, Dept Anat, Chongno Gu, Seoul 110799, South Korea

[2] Sungkyunkwan Univ, Coll Med, Dept Anat, Suwon 440746, South Korea

来源：

BRAIN RESEARCH | 1998年 / 794卷 / 01期

关键词：

iron regulatory protein; Bergmann glia; Purkinje cell; immunohistochemistry; chicken brain;

D O I：

10.1016/S0006-8993(98)00303-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have demonstrated that transferrin binding protein (TfBP), ferritin, and iron, are specifically localized in Bergmann glia, while the transferrin receptor is confined to Purkinje cells in the chicken cerebellum. The results of this study suggest that Bergmann glia have previously undescribed functions related to iron regulation such as sequestration of iron and the maintenance of iron homeostasis in the cerebellum. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：174 / 178

页数：5

共 35 条

[1]

BAEZ M, 1987, J BIOL CHEM, V262, P6582

[2] IMMUNOCYTOCHEMICAL STUDY WITH AN ANTITRANSFERRIN BINDING-PROTEIN SERUM - A MARKER FOR AVIAN OLIGODENDROCYTES [J].

CHO, SS ;

LUCAS, JJ .

BRAIN RESEARCH, 1995, 674 (01) :15-25

[3]

Cho SS, 1997, J COMP NEUROL, V382, P260

[4] CELLULAR-DISTRIBUTION OF TRANSFERRIN, FERRITIN, AND IRON IN NORMAL AND AGED HUMAN BRAINS [J].

CONNOR, JR ;

MENZIES, SL ;

STMARTIN, SM ;

MUFSON, EJ .

JOURNAL OF NEUROSCIENCE RESEARCH, 1990, 27 (04) :595-611

[5] NEURONAL INFLUENCE ON GLIAL ENZYME EXPRESSION - EVIDENCE FROM MUTANT MOUSE CEREBELLA [J].

FISHER, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (14) :4414-4418

[6] BERGMANN GLIA REQUIRE CONTINUOUS ASSOCIATION WITH PURKINJE-CELLS FOR NORMAL PHENOTYPE EXPRESSION [J].

FISHER, M ;

TRIMMER, P ;

RUTHEL, G .

GLIA, 1993, 8 (03) :172-182

[7] DIFFERENTIAL TISSUE LOCALIZATION OF OVIDUCT AND ERYTHROID TRANSFERRIN RECEPTORS [J].

FUERNKRANZ, HA ;

SCHWOB, JE ;

LUCAS, JJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (17) :7505-7508

[8] THE CDNA SEQUENCE AND PRIMARY STRUCTURE OF THE CHICKEN TRANSFERRIN RECEPTOR [J].

GERHARDT, EM ;

CHAN, LNL ;

JING, SQ ;

QI, MY ;

TROWBRIDGE, IS .

GENE, 1991, 102 (02) :249-254

[9] ALTERED BRAIN METABOLISM OF IRON AS A CAUSE OF NEURODEGENERATIVE DISEASES [J].

GERLACH, M ;

BENSHACHAR, D ;

RIEDERER, P ;

YOUDIM, MBH .

JOURNAL OF NEUROCHEMISTRY, 1994, 63 (03) :793-807

[10] ALZHEIMERS-DISEASE - NEUROFIBRILLARY TANGLES IN NUCLEI THAT PROJECT TO THE CEREBRAL-CORTEX [J].

GERMAN, DC ;

WHITE, CL ;

SPARKMAN, DR .

NEUROSCIENCE, 1987, 21 (02) :305-312

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