Comorbid Psychiatric Disorders Associated with Asperger Syndrome/High-functioning Autism: A Community- and Clinic-based Study

被引：248

作者：

Mattila, Marja-Leena ^{[1
]}

Hurtig, Tuula ^{[1
,2
]}

Haapsamo, Helena ^{[1
]}

Jussila, Katja ^{[1
]}

Kuusikko-Gauffin, Sanna ^{[1
]}

Kielinen, Marko ^{[3
]}

Linna, Sirkka-Liisa ^{[1
,2
]}

Ebeling, Hanna ^{[1
]}

Bloigu, Risto ^{[4
]}

Joskitt, Leena ^{[1
]}

Pauls, David L. ^{[5
]}

Moilanen, Irma ^{[1
]}

机构：

[1] Univ Oulu, Clin Child Psychiat, Univ Hosp Oulu, Oulu 90029, Finland

[2] Univ Oulu, Inst Hlth Sci, Oulu 90014, Finland

[3] Univ Oulu, Dept Educ Sci & Teacher Educ, Oulu 90014, Finland

[4] Univ Oulu, Med Informat Grp, Oulu 90014, Finland

[5] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit,Ctr Human Genet Re, Boston, MA 02114 USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2010年 / 40卷 / 09期

关键词：

Comorbidity; CGAS; Asperger syndrome; Autism; Pervasive developmental disorders; Autism spectrum disorders; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; PERVASIVE DEVELOPMENTAL DISORDERS; DEFICIT HYPERACTIVITY DISORDER; SCHOOL-AGE-CHILDREN; SPECTRUM DISORDERS; PREVALENCE; SYMPTOMS; ANXIETY; ADHD; ADOLESCENTS;

D O I：

10.1007/s10803-010-0958-2

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

The present study identifies the prevalence and types of comorbid psychiatric disorders associated with Asperger syndrome (AS)/high-functioning autism (HFA) in a combined community- and clinic-based sample of fifty 9- to 16-year-old subjects using the Schedule for Affective Disorders and Schizophrenia for School-Age Children, Present and Lifetime Version. The level of functioning was estimated using the Children's Global Assessment Scale. The results support common (prevalence 74%) and often multiple comorbid psychiatric disorders in AS/HFA; behavioral disorders were shown in 44%, anxiety disorders in 42% and tic disorders in 26%. Oppositional defiant disorder, major depressive disorder and anxiety disorders as comorbid conditions indicated significantly lower levels of functioning. To target interventions, routine evaluation of psychiatric comorbidity in subjects with AS/HFA is emphasized.

引用

页码：1080 / 1093

页数：14

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