CYP11B2 expression in HSCs and its effect on hepatic fibrogenesis

被引：4
作者：
Li, X [1 ]
Meng, Y
Yang, XS
Wu, PS
Li, SM
Lai, WY
机构：
[1] First Med Univ PLA, Nanfang Hosp, PLA Inst Digest Dis, Guangzhou 510515, Peoples R China
[2] First Med Univ PLA, Nanfang Hosp, Dept Resp Dis, Guangzhou 510515, Peoples R China
[3] First Med Univ PLA, Nanfang Hosp, Dept Cardiol, Guangzhou 510515, Peoples R China
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2000年 / 6卷 / 06期
关键词：
hepatic fibrogenesis; hepatic stellate cells; in situ; hybridization; renin-angiotensin system; aldosterone; polymerase chain reaction; liver cirrosis/prevention and control;
D O I：
10.3748/wjg.v6.i6.885
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：885 / 887
页数：3
相关论文
共 50 条
[11]   Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1 [J].
Takeda, Yoshimichi ;
Demura, Masashi ;
Kometani, Mitsuhiro ;
Karashima, Shigehiro ;
Yoneda, Takashi ;
Takeda, Yoshiyu .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (06)
[12]   Hypomethylation of CYP11B2 in Aldosterone-Producing Adenoma [J].
Yoshii, Yoko ;
Oki, Kenji ;
Gomez-Sanchez, Celso E. ;
Ohno, Haruya ;
Itcho, Kiyotaka ;
Kobuke, Kazuhiro ;
Yoneda, Masayasu .
HYPERTENSION, 2016, 68 (06) :1432-1437
[13]   Disordered zonal and cellular CYP11B2 enzyme expression in familial hyperaldosteronism type 3 [J].
Gomez-Sanchez, Celso E. ;
Qi, Xin ;
Gomez-Sanchez, Elise P. ;
Sasano, Hironobu ;
Bohlen, Martin O. ;
Wisgerhof, Max .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2017, 439 (0C) :74-80
[14]   Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension [J].
Alvarez-Madrazo, Samantha ;
MacKenzie, Scott M. ;
Davies, Eleanor ;
Fraser, Robert ;
Lee, Wai-Kwong ;
Brown, Morris ;
Caulfield, Mark J. ;
Dominiczak, Anna F. ;
Farrall, Martin ;
Lathrop, Mark ;
Hedner, Thomas ;
Melander, Olle ;
Munroe, Patricia B. ;
Samani, Nilesh ;
Stewart, Paul M. ;
Wahlstrand, Bjorn ;
Webster, John ;
Palmer, Colin N. A. ;
Padmanabhan, Sandosh ;
Connell, John M. .
HYPERTENSION, 2013, 61 (01) :232-+
[15]   Structural and clinical characterization of CYP11B2 inhibition by dexfadrostat phosphate [J].
Pignatti, Emanuele ;
Kollar, Jakub ;
Hafele, Evelyn ;
Schuster, Daniela ;
Steele, Ronald E. ;
Vogt, Bruno ;
Schumacher, Christoph ;
Groessl, Michael .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 235
[16]   Mineralocorticoid receptor, CYP11B2 mRNA expression, and atrial matrix remodelling in patients with atrial fibrillation [J].
Pei, De-an ;
Yan, Yan-yue ;
Li, Li ;
Xu, Zhi-yun ;
Huang, Jin-yu ;
Wang, Min ;
Xu, Zheng-ming ;
Yao, Qiang ;
Huang, Shi-eng ;
Huang, Qi ;
Wang, Shi-sheng .
ACTA CARDIOLOGICA, 2010, 65 (05) :527-533
[17]   Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors [J].
Meredith, Erik L. ;
Ksander, Gary ;
Monovich, Lauren G. ;
Papillon, Julien P. N. ;
Liu, Qian ;
Miranda, Karl ;
Morris, Patrick ;
Rao, Chang ;
Burgis, Robin ;
Capparelli, Michael ;
Hu, Qi-Ying ;
Singh, Alok ;
Rigel, Dean F. ;
Jeng, Arco Y. ;
Beil, Michael ;
Fu, Fumin ;
Hu, Chii-Whei ;
LaSala, Daniel .
ACS MEDICINAL CHEMISTRY LETTERS, 2013, 4 (12) :1203-1207
[18]   Identification of sulfonylpyrimidines as novel selective aldosterone synthase (CYP11B2) inhibitors [J].
Meguro, Masaki ;
Miyauchi, Satoru ;
Kanao-Arisumi, Yukiko ;
Naito, Satoru ;
Suzuki, Kanae ;
Inoue, Shinichi ;
Yamada, Keisuke ;
Homma, Tsuyoshi ;
Chiba, Kiyoshi ;
Nara, Futoshi ;
Furuzono, Shinji .
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 108
[19]   A ubiquitin-proteasome inhibitor bortezomib suppresses the expression of CYP11B2, a key enzyme of aldosterone synthesis [J].
Ito, Ryo ;
Sato, Ikuko ;
Tsujita, Tadayuki ;
Yokoyama, Atsushi ;
Sugawara, Akira .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 489 (01) :21-28
[20]   High aldosterone-to-renin variants of CYP11B2 and pregnancy outcome [J].
Escher, Genevieve ;
Cristiano, Martino ;
Causevic, Maja ;
Baumann, Marc ;
Frey, Felix J. ;
Surbek, Daniel ;
Mohaupt, Markus G. .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 24 (06) :1870-1875
12345