Methylation - an uncommon modification of glycans

被引:50
作者
Staudacher, Erika [1 ]
机构
[1] Univ Nat Resources & Life Sci, Dept Chem, A-1190 Vienna, Austria
基金
奥地利科学基金会;
关键词
glycan; methylation; sugar; N-LINKED OLIGOSACCHARIDES; SNAIL BIOMPHALARIA-GLABRATA; STRUCTURAL-CHARACTERIZATION; LYMNAEA-STAGNALIS; 3-O-METHYL-D-GALACTOSE RESIDUES; MYCOBACTERIUM-SMEGMATIS; CAENORHABDITIS-ELEGANS; PECTIC POLYSACCHARIDE; CARBOHYDRATE CHAINS; O-POLYSACCHARIDE;
D O I
10.1515/hsz-2012-0132
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A methyl (Me) group on a sugar residue is a rarely reported event. Until now, this type of modification has been found in the animal kingdom only in worms and molluscs, whereas it is more frequently present in some species of bacteria, fungi, algae and plants, but not in mammals. The monosaccharides involved as well as the positions of the Me groups on the sugar vary with species. Methylation appears to play a role in some recognition events, but details are still unknown. This review summarises the current knowledge on methylation of sugars in all types of organism.
引用
收藏
页码:675 / 685
页数:11
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