Ultrasound-Guided Intratendinous Injections With Platelet-Rich Plasma or Autologous Whole Blood for Treatment of Proximal Hamstring Tendinopathy

被引:45
作者
Davenport, Kathleen L. [1 ]
Campos, Jose Santiago [2 ]
Nguyen, Joseph [3 ]
Saboeiro, Gregory [4 ]
Adler, Ronald S. [6 ]
Moley, Peter J. [5 ]
机构
[1] Preferred Orthoped Palm Beaches, Boynton Beach, FL USA
[2] Carteret Comprehens Med Care, PC, Carteret, NJ USA
[3] Hosp Special Surg, Dept Epidemiol & Biostat, New York, NY 10021 USA
[4] Hosp Special Surg, Dept Radiol & Imaging, New York, NY 10021 USA
[5] Hosp Special Surg, Dept Physiatry, New York, NY 10021 USA
[6] NYU, Langone Med Ctr, Dept Radiol & Imaging, New York, NY USA
关键词
hamstring; musculoskeletal ultrasound; platelet-rich plasma; ultrasound; whole blood; RANDOMIZED CONTROLLED-TRIAL; LATERAL EPICONDYLITIS; CORTICOSTEROID INJECTION; ACHILLES TENDINOPATHY; SURGICAL-MANAGEMENT; INJURIES; TENDON; HIP;
D O I
10.7863/ultra.34.8.1455
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Objectives-To compare the effects of Ultrasound-guided platelet-rich plasma (PRP) and whole blood (WB) injections in patients with chronic hamstring tendinopathy. Methods-In a prospective double-blind randomized controlled trial, PRP or WB was injected under ultrasound guidance into the proximal hamstring tendon in a cohort of patients with clinically suspected hamstring tendinosis. Questionnaires were administered before injection and 2, 6, and 12 weeks and 6 months after injection. Pain and function outcomes were measured via the Modified Harris Hip Score (MHHS), Hip Outcome Scores for activities of daily living (ADL) and sport-specific function, and International Hip Outcome Tool 33 (IHOT-33). Diagnostic ultrasound was used to compare preinjection and 6-month postinjection tendon appearances. Results-The WB group showed greater improvements in pain and function over the PRP group before 12 weeks, whereas the PRP group showed improved outcomes over WB at 6 months. None of these between-group outcome measures, except 6-week IHOT-33, showed statistical significance. Comparing preinjection and 6-month scores, the PRP group showed significant improvements in ADL (P = .018) and IHOT-33 (P = .28) scores, whereas the WB group showed no significant improvements from baseline. The WB group showed significantly decreased pain with 15-minute sitting (P = .008) at 6 months. Ultrasound imaging showed no significant differences between PRP and WB group tendon appearances. Conclusions-Both PRP and WB groups showed improvements in all outcome measures at 6 months. The PRP group showed significant improvements in 6-month ADL and IHOT-33 scores. The WB group reached significance in 15-minute sitting pain. No significant between-group differences were observed at any time point.
引用
收藏
页码:1455 / 1463
页数:9
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