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Ultrasound-Guided Intratendinous Injections With Platelet-Rich Plasma or Autologous Whole Blood for Treatment of Proximal Hamstring Tendinopathy
被引:45
作者:
Davenport, Kathleen L.
[1
]
Campos, Jose Santiago
[2
]
Nguyen, Joseph
[3
]
Saboeiro, Gregory
[4
]
Adler, Ronald S.
[6
]
Moley, Peter J.
[5
]
机构:
[1] Preferred Orthoped Palm Beaches, Boynton Beach, FL USA
[2] Carteret Comprehens Med Care, PC, Carteret, NJ USA
[3] Hosp Special Surg, Dept Epidemiol & Biostat, New York, NY 10021 USA
[4] Hosp Special Surg, Dept Radiol & Imaging, New York, NY 10021 USA
[5] Hosp Special Surg, Dept Physiatry, New York, NY 10021 USA
[6] NYU, Langone Med Ctr, Dept Radiol & Imaging, New York, NY USA
关键词:
hamstring;
musculoskeletal ultrasound;
platelet-rich plasma;
ultrasound;
whole blood;
RANDOMIZED CONTROLLED-TRIAL;
LATERAL EPICONDYLITIS;
CORTICOSTEROID INJECTION;
ACHILLES TENDINOPATHY;
SURGICAL-MANAGEMENT;
INJURIES;
TENDON;
HIP;
D O I:
10.7863/ultra.34.8.1455
中图分类号:
O42 [声学];
学科分类号:
070206 ;
082403 ;
摘要:
Objectives-To compare the effects of Ultrasound-guided platelet-rich plasma (PRP) and whole blood (WB) injections in patients with chronic hamstring tendinopathy. Methods-In a prospective double-blind randomized controlled trial, PRP or WB was injected under ultrasound guidance into the proximal hamstring tendon in a cohort of patients with clinically suspected hamstring tendinosis. Questionnaires were administered before injection and 2, 6, and 12 weeks and 6 months after injection. Pain and function outcomes were measured via the Modified Harris Hip Score (MHHS), Hip Outcome Scores for activities of daily living (ADL) and sport-specific function, and International Hip Outcome Tool 33 (IHOT-33). Diagnostic ultrasound was used to compare preinjection and 6-month postinjection tendon appearances. Results-The WB group showed greater improvements in pain and function over the PRP group before 12 weeks, whereas the PRP group showed improved outcomes over WB at 6 months. None of these between-group outcome measures, except 6-week IHOT-33, showed statistical significance. Comparing preinjection and 6-month scores, the PRP group showed significant improvements in ADL (P = .018) and IHOT-33 (P = .28) scores, whereas the WB group showed no significant improvements from baseline. The WB group showed significantly decreased pain with 15-minute sitting (P = .008) at 6 months. Ultrasound imaging showed no significant differences between PRP and WB group tendon appearances. Conclusions-Both PRP and WB groups showed improvements in all outcome measures at 6 months. The PRP group showed significant improvements in 6-month ADL and IHOT-33 scores. The WB group reached significance in 15-minute sitting pain. No significant between-group differences were observed at any time point.
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页码:1455 / 1463
页数:9
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