How to Image Cardiac Amyloidosis A Practical Approach

被引:181
作者
Dorbala, Sharmila [1 ,2 ,3 ]
Cuddy, Sarah [1 ,2 ,3 ]
Falk, Rodney H. [3 ]
机构
[1] Brigham & Womens Hosp, Dept Radiol, Div Nucl Med, 75 Francis St, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Cardiovasc Div, CV Imaging Program, 75 Francis St, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Med, Div Cardiol, Cardiac Amyloidosis Program, Boston, MA USA
基金
美国国家卫生研究院;
关键词
amyloid tracers; cardiac amyloidosis; cardiac magnetic resonance; CMR; echocardiography; imaging; multimodality; radionuclide imaging; PET; pyrophosphate; Tc-99m-PYP; AL AMYLOIDOSIS; SYSTEMIC AMYLOIDOSIS; MAGNETIC-RESONANCE; HEART-FAILURE; MICROVASCULAR DYSFUNCTION; LIGHT-CHAINS; TRANSTHYRETIN; DIAGNOSIS; CMR; QUANTIFICATION;
D O I
10.1016/j.jcmg.2019.07.015
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with a median survival from diagnosis, if untreated, ranging from <6 months for light chain amyloidosis to 3 to 5 years for transthyretin amyloidosis. Early diagnosis and accurate typing of CA are necessary for optimal management of these patients. Emerging novel disease modifying therapies increase the urgency to diagnose CA at an early stage and identify patients who may benefit from these life-saving therapies. The goal of this review is to provide a practical approach to echocardiography, cardiac magnetic resonance, and radionuclide imaging in patients with known or suspected CA. (c) 2020 by the American College of Cardiology Foundation.
引用
收藏
页码:1368 / 1383
页数:16
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