A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells

被引:83
作者
Calimeri, T. [1 ,2 ]
Battista, E. [3 ,4 ]
Conforti, F. [5 ]
Neri, P. [1 ,2 ,6 ]
Di Martino, M. T. [1 ,2 ]
Rossi, M. [1 ,2 ]
Foresta, U. [1 ,2 ]
Piro, E. [7 ]
Ferrara, F. [8 ]
Amorosi, A. [5 ]
Bahlis, N. [6 ]
Anderson, K. C. [9 ,10 ]
Munshi, N. [9 ,10 ]
Tagliaferri, P. [1 ,2 ]
Causa, F. [3 ,4 ]
Tassone, P. [1 ,2 ]
机构
[1] Univ Magna Gracia, Dept Expt & Clin Med, Translat Med Oncol Unit, Catanzaro, Italy
[2] Tommaso Campanella Canc Ctr, Catanzaro, Italy
[3] Univ Magna Gracia, Dept Expt & Clin Med, Biomat Lab, Catanzaro, Italy
[4] Italian Inst Technol, Ctr Adv Biomat Hlth Care, Naples, Italy
[5] Univ Magna Gracia, Dept Pathol, Sch Med, Catanzaro, Italy
[6] Univ Calgary, Dept Med, Hematol Unit, Calgary, AB, Canada
[7] Azienda Osped Pugliese Ciaccio, Hematol Unit, Catanzaro, Italy
[8] Villa Serena Hosp, Orthoped Surg Unit, Catanzaro, Italy
[9] Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA
[10] Harvard Univ, Sch Med, Boston, MA USA
关键词
D O I
10.1038/leu.2010.300
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:707 / 711
页数:5
相关论文
共 8 条
  • [1] Poly-ε-caprolactone/hydroxyapatite composites for bone regeneration:: in vitro characterization and human osteoblast response
    Causa, F
    Netti, PA
    Ambrosio, L
    Ciapetti, G
    Baldini, N
    Pagani, S
    Martini, D
    Giunti, A
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2006, 76A (01) : 151 - 162
  • [2] Synopsis of a roundtable on validating novel therapeutics for multiple myeloma
    Dalton, William
    Anderson, Kenneth C.
    [J]. CLINICAL CANCER RESEARCH, 2006, 12 (22) : 6603 - 6610
  • [3] Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
    Fulciniti, Mariateresa
    Tassone, Pierfrancesco
    Hideshima, Teru
    Vallet, Sonia
    Nanjappa, Puru
    Ettenberg, Seth A.
    Shen, Zhenxin
    Patel, Nipun
    Tai, Yu-tzu
    Chauhan, Dharminder
    Mitsiades, Constantine
    Prabhala, Rao
    Raje, Noopur
    Anderson, Kenneth C.
    Stover, David R.
    Munshi, Nikhil C.
    [J]. BLOOD, 2009, 114 (02) : 371 - 379
  • [4] Drug therapy: Multiple myeloma
    Kyle, RA
    Rajkumar, SV
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (18) : 1860 - 1873
  • [5] A clinically relevant SCID-hu in vivo model of human multiple myeloma
    Tassone, P
    Neri, P
    Carrasco, DR
    Burger, R
    Goldmacher, VS
    Fram, R
    Munshi, V
    Shammas, MA
    Catley, L
    Jacob, GS
    Venuta, S
    Anderson, KC
    Munshi, NC
    [J]. BLOOD, 2005, 106 (02) : 713 - 716
  • [6] Novel therapeutic approaches based on the targeting of microenvironment-derived survival pathways in human cancer: Experimental models and translational issues
    Tassone, Pierfrancesco
    Tagliaferri, Pierosandro
    Fulciniti, Maria Teresa
    Di Martino, Maria Teresa
    Venuta, Salvatore
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2007, 13 (05) : 487 - 496
  • [7] The development of a model for the homing of multiple myeloma cells to human bone marrow
    Urashima, M
    Chen, BP
    Chen, S
    Pinkus, GS
    Bronson, RT
    Dedera, DA
    Hoshi, Y
    Teoh, G
    Ogata, A
    Treon, SP
    Chauhan, D
    Anderson, KC
    [J]. BLOOD, 1997, 90 (02) : 754 - 765
  • [8] Primary myeloma cells growing in SCID-hu mice: A model for studying the biology and treatment of myeloma and its manifestations
    Yaccoby, S
    Barlogie, B
    Epstein, J
    [J]. BLOOD, 1998, 92 (08) : 2908 - 2913