Strigolactam: New potent strigolactone analogues for the germination of Orobanche cumana

被引：46

作者：

Lachia, Mathilde ^{[1
]}

Wolf, Hanno Christian ^{[2
]}

Jung, Pierre Joseph Marcel ^{[1
]}

Screpanti, Claudio ^{[2
]}

De Mesmaeker, Alain ^{[1
]}

机构：

[1] Syngenta Crop Protect AG, Crop Protect Res, Res Chem, CH-4332 Stein, Switzerland

[2] Syngenta Crop Protect AG, Crop Protect Res, Res Biol, CH-4332 Stein, Switzerland

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2015年 / 25卷 / 10期

关键词：

Strigolactones; Orobanche cumana; Seed germination induction; Ketene-iminium salts; Cyclobutanones; INTRAMOLECULAR 2+2 CYCLOADDITION; PARASITIC WEEDS STRIGA; ASYMMETRIC-SYNTHESIS; MOLECULAR-MECHANISM; SEED-GERMINATION; PLANT; INHIBITION; BECKMANN; SIGNAL; STEREOISOMERS;

D O I：

10.1016/j.bmcl.2015.03.056

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Very recently, strigolactones have been conclusively identified as phytohormones. The progresses achieved in this field are culminating in the identification of the molecular receptors involved in the signal transduction mechanism. The exact mechanism of the mode of action of strigolactones still remains to be fully elucidated and we were interested to gain some insight into the mechanism of action of strigolactones by selectively modifying the reactivity of the lactone C-ring. Therefore, we report here the synthesis of strigolactams 1 and 16 and their surprisingly good activity on the germination of Orobanche cumana parasitic weed seeds. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：2184 / 2188

页数：5

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