The 3D Bioprinted Scaffolds for Wound Healing

被引:63
作者
Antezana, Pablo Edmundo [1 ]
Municoy, Sofia [1 ]
Alvarez-Echazu, Maria Ines [1 ]
Santo-Orihuela, Pablo Luis [1 ,2 ]
Catalano, Paolo Nicolas [1 ,3 ]
Al-Tel, Taleb H. [4 ,5 ]
Kadumudi, Firoz Babu [6 ]
Dolatshahi-Pirouz, Alireza [6 ]
Orive, Gorka [7 ,8 ,9 ,10 ,11 ]
Desimone, Martin Federico [1 ]
机构
[1] Univ Buenos Aires, Consejo Nacl Invest Cient & Tecn CONICET, Fac Farm & Bioquim, Inst Quim & Metab Farmaco IQUIMEFA, Junin 956, RA-1113 Buenos Aires, DF, Argentina
[2] Argentina CONICET, Consejo Nacl Invest Cient & Tecn, Ctr Invest Plagas & Insecticidas CIPEIN, Inst Invest Cient & Tecn Defensa CITEDEF UNIDEF, Juan B Salle 4397, RA-1603 Buenos Aires, DF, Argentina
[3] Consejo Nacl Invest Cient & Tecn, CNEA, Inst Nanociencia & Nanotecnol, Dept Micro & Nanotecnol, Av Gen Paz 1499, RA-1650 San Martin, Argentina
[4] Univ Sharjah, Sharjah Inst Med Res, POB 27272, Sharjah, U Arab Emirates
[5] Univ Sharjah, Coll Pharm, POB 27272, Sharjah, U Arab Emirates
[6] Tech Univ Denmark, Dept Hlth Technol, DK-2800 Kongens Lyngby, Denmark
[7] Univ Basque Country, UPV EHU, Sch Pharm, NanoBioCel Grp,Lab Pharmaceut, Paseo Univ 7, Vitoria 01006, Spain
[8] Biomed Res Networking Ctr Bioengn Biomat & Nanome, Vitoria 01006, Spain
[9] Bioaraba, NanoBioCel Res Grp, Vitoria 01006, Spain
[10] Univ Inst Regenerat Med & Oral Implantol UIRMI, UPV EHU, Fdn Eduardo Anitua, Vitoria 01007, Spain
[11] Singapore Eye Res Inst, Acad, 20 Coll Rd,Discovery Tower, Singapore 169856, Singapore
关键词
tissue engineering; three-dimensional bioprinted scaffolds; wound healing; three-dimensional printing technology; bioinks; HUMAN SKIN; TISSUE REGENERATION; ARTIFICIAL BONES; CELL-TYPES; IN-VITRO; STEREOLITHOGRAPHY; FABRICATION; HYDROGELS; COLLAGEN; CONSTRUCTS;
D O I
10.3390/pharmaceutics14020464
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Skin tissue engineering and regeneration aim at repairing defective skin injuries and progress in wound healing. Until now, even though several developments are made in this field, it is still challenging to face the complexity of the tissue with current methods of fabrication. In this review, short, state-of-the-art on developments made in skin tissue engineering using 3D bioprinting as a new tool are described. The current bioprinting methods and a summary of bioink formulations, parameters, and properties are discussed. Finally, a representative number of examples and advances made in the field together with limitations and future needs are provided.
引用
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页数:46
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