Gold-Nanosponge-Based Multistimuli-Responsive Drug Vehicles for Targeted Chemo-Photothermal Therapy

被引：160

作者：

Zheng, Tingting ^{[1
,2
]}

Li, Guangfang Grace ^{[2
]}

Zhou, Fei ^{[1
]}

Wu, Rong ^{[1
]}

Zhu, Jun-Jie ^{[1
]}

Wang, Hui ^{[2
]}

机构：

[1] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China

[2] Univ South Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA

来源：

ADVANCED MATERIALS | 2016年 / 28卷 / 37期

基金：

美国国家科学基金会; 中国国家自然科学基金;

关键词：

cancer; chemo-photothermal therapy; drug delivery; nanomedicine; nanoparticles; NEAR-INFRARED LIGHT; MESOPOROUS SILICA NANOPARTICLES; CANCER-CELLS; MULTIFUNCTIONAL NANOPARTICLES; OPTICAL-PROPERTIES; CONTROLLED-RELEASE; DOXORUBICIN; NANOSPHERES; NANOCAGES; DELIVERY;

D O I：

10.1002/adma.201602486

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gold-nanosponge-based multistimuli-responsive drug vehicles are constructed for combined chemo-photothermal therapy with pinpointed drug delivery and release capabilities and minimized nonspecific systemic spread of drugs, remarkably enhancing the therapeutic efficiency while minimizing acute side effects.

引用

页码：8218 / 8226

页数：9

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