Paracoccidioidomycosis

被引：69

作者：

Marques, Silvio Alencar ^{[1
]}

机构：

[1] Sao Paulo State Univ UNESP, Botucatu Med Sch, Dept Dermatol & Radiotherapy, BR-18600010 Sao Paulo, Brazil

来源：

CLINICS IN DERMATOLOGY | 2012年 / 30卷 / 06期

关键词：

BRASILIENSIS; ASSOCIATION; DIAGNOSIS;

D O I：

10.1016/j.clindermatol.2012.01.006

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Paracoccidioidomycosis is an endemic systemic mycosis that predominates in southern Mexico, parts of Central America, and South America. It is caused by a dimorphic fungus and is generally acquired through the lungs, from where it disseminates. Paracoccidioidomycosis has different clinical manifestations that require differentiation with tuberculosis, Hodgkin disease, several systemic and subcutaneous mycoses, and squamous cell carcinoma. Diagnosis is made by finding the organism in a biopsy specimen and isolating it in fungal culture. Treatment includes sulfamethoxazole-trimethoprim for mild forms and itraconazole for moderate cases. Fluconazole and voriconazole can be used for meningeal involvement, and amphotericin B is indicated for severe disease. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：610 / 615

页数：6

共 29 条

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