Lignin-Based Micro- and Nanomaterials and their Composites in Biomedical Applications

被引：177

作者：

Liu, Rui ^{[1
,2
]}

Dai, Lin ^{[1
]}

Xu, Chunlin ^{[2
]}

Wang, Kai ^{[3
]}

Zheng, Chunyang ^{[4
]}

Si, Chuanling ^{[1
]}

机构：

[1] Tianjin Univ Sci & Technol, Tianjin Key Lab Pulp & Paper, TEDA, 9 13th Ave, Tianjin 300457, Peoples R China

[2] Abo Akad Univ, Lab Nat Mat Technol, Johan Gadolin Proc Chem Ctr, Turku 20500, Finland

[3] Tianjin Hosp, Int Med Ctr, 506 Jiefang South Rd, Tianjin, Peoples R China

[4] Robustn Co Ltd, Block C,Phase 2,Pioneer Pk,Lanyuan Rd, Tianjin 300384, Peoples R China

来源：

CHEMSUSCHEM | 2020年 / 13卷 / 17期

基金：

中国国家自然科学基金;

关键词：

biomass; biomedical industry; hydrogels; lignin; nanomaterials; KRAFT LIGNIN; CARBON DOTS; IN-VITRO; POLYMERIC NANOPARTICLES; ANTIOXIDANT PROPERTIES; EFFICIENT DELIVERY; CONTROLLED-RELEASE; GREEN SYNTHESIS; DRUG-DELIVERY; STRAW LIGNIN;

D O I：

10.1002/cssc.202000783

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lignin, as the most abundant aromatic renewable biopolymer in nature, has long been regarded as waste and simply discarded from the pulp and paper industry. In recent years, with many breakthroughs in lignin chemistry, pretreatment, and processing techniques, a lot of the inherent bioactivities of lignin, including antioxidant activities, antimicrobial activities, biocompatibilities, optical properties, and metal-ion chelating and redox activities, have been discovered and this has opened a new field not only for lignin-based materials but also for biomaterials. In this Review, the biological activities of lignin and drug/gene delivery and bioimaging applications of various types of lignin-based material are summarized. In addition, the challenges and limitations of lignin-based materials encountered during the development of biomedical applications are also discussed.

引用

页码：4266 / 4283

页数：18

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