Synthesis and antibacterial activity of sulfonamide derivatives at C-8 alkyl chain of anacardic acid mixture isolated from a natural product cashew nut shell liquid (CNSL)

被引：23

作者：

Reddy, N. Subhakara ^{[3
,4
]}

Rao, A. Srinivas ^{[3
]}

Chari, M. Adharvana ^{[1
,2
]}

Kumar, V. Ravi ^{[3
]}

Jyothy, V. ^{[1
]}

Himabindu, V. ^{[4
]}

机构：

[1] Dr MACS Biopharma Pvt Ltd, Hyderabad 500085, Andhra Pradesh, India

[2] Univ Tokyo, Dept Complex Sci & Engn, Sch Frontier Sci, Chiba 2778561, Japan

[3] GVK Biosci Pvt Ltd, Med Chem Lab, IDA, Hyderabad 500039, Andhra Pradesh, India

[4] JNT Univ, Ctr Environm, Inst Sci & Technol, Hyderabad 500085, Andhra Pradesh, India

来源：

JOURNAL OF CHEMICAL SCIENCES | 2012年 / 124卷 / 03期

关键词：

Synthesis; sulfonamide derivatives; anacardic acid; antibacterial activity; HISTONE ACETYLTRANSFERASE; PHENOLIC CONSTITUENTS; INHIBITION; RESISTANCE; EXPRESSION; AGENTS; KINASE;

D O I：

10.1007/s12039-012-0253-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis and antibacterial activity of some novel biologically active sulfonamide derivatives at C-8 alkyl chain of anacardic acid (7a-7l), prepared from commercially available anacardic acid mixture (1a-d). These compounds were tested for Gram positive and Gram negative bacterial cultures; most of the compounds showed higher antibacterial activity compared with standard drug ampicillin.

引用

页码：723 / 730

页数：8

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