Placental characteristics in growth-discordant monochorionic twins: A matched case-control study

被引：39
作者：
Lopriore, E. [1 ]
Pasman, S. A. [2 ]
Klumper, F. J. [2 ]
Middeldorp, J. M. [2 ]
Walther, F. J. [1 ]
Oepkes, D. [2 ]
机构：
[1] Leiden Univ, Med Ctr, Div Neonatol, Dept Pediat, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ, Med Ctr, Div Fetal Med, Dept Obstet, NL-2300 RC Leiden, Netherlands
来源：
PLACENTA | 2012年 / 33卷 / 03期
关键词：
Monochorionic placentas; Birth weight discordance; Selective intrauterine growth restriction; Arterio-arterial anastomosis; Velamentous cord insertion; Placental sharing; PREGNANCIES; CLASSIFICATION; RESTRICTION; PATHOLOGY;
D O I：
10.1016/j.placenta.2011.12.004
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Objective: To compare the placental characteristics in monochorionic (MC) twin pregnancies with and without birth weight discordance (BWD). Methods: We performed a matched case-control study to compare the placental characteristics of MC placentas from pregnancies with BWD (>= 25%) (n = 47) with a control group of MC placentas without BWD (n = 47), matched for gestational age at birth. Placental sharing, angioarchitecture and diameter of the arterio-arterial (AA) anastomosis were assessed by placental injection with colored dye. Results: The rate of velamentous cord insertion in MC placentas with and without BWD was 30% (28/94) and 16% (15/94), respectively (p = 0.036). Placental sharing discordance in MC placentas with and without BWD was 36% and 17%, respectively (p < 0.001). The mean diameter of the M anastomosis in MC placentas with and without BWD was 2.2 mm and 1.8 mm, respectively (p = 0.024). Conclusion: MC placentas from growth-discordant twins are more unequally shared, have a higher rate of velamentous cord insertions and larger diameter of AA anastomosis compared to gestational age matched controls. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：171 / 174
页数：4
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