Reactivity of 2-substituted hydrazinecarbothioamides towards tetracyanoethylene and convenient synthesis of (5-amino-2-diazenylthiazolylmethylene) malononitrile derivatives

被引：2

作者：

Hassan, Alaa A. ^{[1
]}

Mohamed, Nasr K. ^{[1
]}

El-Shaieb, Kamal M. A. ^{[1
]}

Tawfeek, Hendawy N. ^{[1
]}

Braese, Stefan ^{[2
]}

Nieger, Martin ^{[3
]}

机构：

[1] Menia Univ, Dept Chem, Fac Sci, El Minia 61519, Egypt

[2] Karlsruhe Inst Technol, Inst Organ Chem, Fritz Haber Weg 6, D-76131 Karlsruhe, Germany

[3] Univ Helsinki, Dept Chem, Inorgan Chem Lab, POB 55,AI Virtasen Aukio 1, FIN-00014 Helsinki, Finland

来源：

ARKIVOC | 2016年

关键词：

Malononitrile; thiazoles; thiosemicarbazides; tetracyanoethylene; X-ray crystallography; THIAZOLE; 5-AMINOTHIAZOLES; ANTIBACTERIAL; INHIBITORS; SERIES;

D O I：

10.3998/ark.5550190.p009.872

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-{Amino-[5-amino-2-(substituted diazenyl) thiazol-4-yl] methylene} malononitriles were synthesized from the reaction of 2-substituted hydrazinecarbothioamides with tetracyanoethylene (TCNE) to give tetracyanoethane adduct, followed by heterocyclization afforded the target compounds. The structure of (E)-2-{amino-[5-amino-2-(phenyldiazenyl) thiazol-4-yl] methylene} malononitrile was supported by single crystal X-ray crystallography.

引用

页码：163 / 171

页数：9

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