Harnessing the Therapeutic Potential of the Adaptive ATF6 Branch of the Unfolded Protein Response

被引：0
|
作者：
Sarakki, Anup, V [1 ]
Blackwood, Erik A. [1 ]
Thuerauf, Donna J. [1 ]
Azizi, Khalid [1 ]
Dorougdar, Shirin [2 ]
Glembotski, Christopher C. [1 ]
机构：
[1] San Diego State Univ, Biol, San Diego, CA 92182 USA
[2] Univ Hosp Heidelberg, Innere Med 3, Heidelberg, Germany
来源：
CIRCULATION | 2018年 / 138卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A16323
引用
收藏
页数：2
相关论文
共 50 条
  • [11] Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response
    Hong, M
    Luo, SZ
    Baumeister, P
    Huang, JM
    Gogia, RK
    Li, MQ
    Lee, AS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (12) : 11354 - 11363
  • [12] Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation
    Tsukumo, Yoshinori
    Tomida, Akihiro
    Kitahara, Osamu
    Nakamura, Yusuke
    Asada, Shinichi
    Mori, Kazutoshi
    Tsuruo, Takashi
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (40) : 29264 - 29272
  • [13] Molecular mechanism of ATF6 in unfolded protein response and its role in disease
    Lei, Yingying
    Yu, Hong
    Ding, Shaoxue
    Liu, Hui
    Liu, Chunyan
    Fu, Rong
    HELIYON, 2024, 10 (05)
  • [14] SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6
    Hou, Xia
    Yang, Zhao
    Zhang, Kezhong
    Fang, Deyu
    Sun, Fei
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 494 (3-4) : 446 - 451
  • [15] Activation of the Akt-NF-κB Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response
    Yamazaki, Hiroaki
    Hiramatsu, Nobuhiko
    Hayakawa, Kunihiro
    Tagawa, Yasuhiro
    Okamura, Maro
    Ogata, Ryouji
    Huang, Tao
    Nakajima, Shotaro
    Yao, Jian
    Paton, Adrienne W.
    Paton, James C.
    Kitamura, Masanori
    JOURNAL OF IMMUNOLOGY, 2009, 183 (02): : 1480 - 1487
  • [16] ERp18 regulates activation of ATF6α during unfolded protein response
    Oka, Ojore B. V.
    van Lith, Marcel
    Rudolf, Jana
    Tungkum, Wanida
    Pringle, Marie Anne
    Bulleid, Neil J.
    EMBO JOURNAL, 2019, 38 (15):
  • [17] Partial limitation of cellular functions and compensatory modulation of unfolded protein response pathways caused by double-knockout of ATF6α and ATF6β
    Akai, Ryoko
    Hamashima, Hisayo
    Saito, Michiko
    Kohno, Kenji
    Iwawaki, Takao
    CELL STRESS & CHAPERONES, 2024, 29 (01): : 34 - 48
  • [18] ATF6, a key regulator of the unfolded protein response, is associated with type 2 diabetes
    Meex, S. J. R.
    van Greevenbroek, M. M. J.
    Ayoubi, T. A.
    Vlietinck, R.
    Vermeulen, V. M. M.
    Feskens, E.
    Schalkwijk, C. G.
    Stehouwer, C. D. A.
    van der Kallen, C. J. H.
    de Bruin, T. W. A.
    DIABETOLOGIA, 2006, 49 : 208 - 208
  • [19] Unfolded Protein Response Regulator, ATF6, is Essential for Stress Survival in Cone Photoreceptors
    Chiang, Wei-Chieh Jerry
    Bi, Xiaoke
    Kroeger, Heike
    Landeros, Stephanie
    Cheng, Lingyun
    Lin, Jonathan H.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [20] Functional Diversity of Novel Disease Mutations in the Unfolded Protein Response regulator, ATF6
    Chiang, Wei-Chieh
    Chan, Priscilla
    Lin, Jonathan H.
    FASEB JOURNAL, 2016, 30
12345