共 2 条
- [2] Analysis of electrochemical reaction of ferrocenylnaphthalene diimide captured by double-stranded DNA during the electrochemical detection of DNA hybridizationELECTROCHEMISTRY, 2006, 74 (01) : 65 - 67Komatsu, MNojima, TTakenaka, S
Supramolecular complex formation by β-cyclodextrin and ferrocenylnaphthalene diimide-intercalated double stranded DNA and improved electrochemical gene detection
被引：36
|作者：
Sato, S
[1
]
Nojima, T
[1
]
Waki, M
[1
]
Takenaka, S
[1
]
机构：
[1] Kyushu Inst Technol, Dept Mat Sci, Tobata Ku, Kitakyushu, Fukuoka 8048550, Japan
来源：
MOLECULES
|
2005年
/
10卷
/
06期
关键词：
ferrocenylnaphthalene diimide;
beta-cyclodextrin (CD);
DNA;
electrochemical detection;
supramolecular complex;
D O I：
10.3390/10060693
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
Ferrocenylnaphthalene diimide 1 can bind to double stranded DNA (dsDNA) by the threading intercalation mode and the resulting complex was stabilized further by beta-cyclodextrin (CD) by forming a supramolecular complex. These complex formation processes were studied by spectroscopic, viscometric, and electrochemical means in the absence or presence of beta-CD. Quantitative analysis by quartz crystal microbalance (QCM) and electrochemical experiments strongly suggested a 2:1 binding stoichiometry for beta-CD to 1 threading-intercalated to the dsDNA-immobilized electrode. Owing to this supramolecular complex formation, electrochemical DNA detection based on 1 was improved considerably.
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页码：693 / 707
页数：15
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