Severe thrombocytopenia induced by a single infusion of trastuzumab

被引：15

作者：

Parikh, Omi ^{[1
]}

Neave, Farhad ^{[2
]}

Palmieri, Carlo ^{[3
]}

机构：

[1] Royal Preston Hosp, London, England

[2] N Middlesex Univ Hosp, London, England

[3] Univ London St Georges Hosp, London, England

来源：

CLINICAL BREAST CANCER | 2008年 / 8卷 / 03期

关键词：

HER2; lymphadenopathy; petechial rash; tamoxifen;

D O I：

10.3816/CBC.2008.n.034

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a case of severe thrombocytopenia related to adjuvant trastuzumab use. Less than 24 hours after administration of her first dose of single-agent trastuzumab, the patient was admitted to the hospital with a platelet count of 2 x 10(9)/L. Trastuzumab is being increasingly used and, to our knowledge, severe thrombocytopenia has not yet been reported as an adverse event. This case highlights a serious and potentially life-threatening complication with the use of single-agent trastuzumab.

引用

页码：285 / 286

页数：2

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