Prognostic value of serum progesterone and LH values on the day of hCG administration in IUI GnRH antagonist cycles

被引：6

作者：

Matorras, R. ^{[2
,3
]}

Valls i Soler, A.

Ramon, O. ^{[4
]}

Burgos, J. ^{[4
]}

Abanto, E. ^{[4
]}

Gonzalez, M. ^{[4
]}

Mugica, J. ^{[5
]}

Corcostegui, B. ^{[4
]}

Pijoan, J. I. ^{[6
]}

Exposito, Antonia ^{[1
]}

机构：

[1] Cruces Hosp, Baracaldo, Spain

[2] Sch Med, Bizkaia, Spain

[3] Neonatal Intens Care Unit, Bizkaia, Spain

[4] Assisted Reprod Unit, Bizkaia, Spain

[5] Lab Endocrinol, Bizkaia, Spain

[6] Clin Epidemiol Unit, Bizkaia, Spain

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2012年 / 28卷 / 03期

关键词：

Assisted reproductive technology; pregnancy; infertility; IN-VITRO FERTILIZATION; STIMULATED INTRAUTERINE INSEMINATION; CONTROLLED OVARIAN HYPERSTIMULATION; PREMATURE LUTEINIZATION; RANDOMIZED-TRIAL; CLOMIPHENE CITRATE; GONADOTROPIN; HORMONE; PREGNANCY; MULTICENTER;

D O I：

10.3109/09513590.2011.588747

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objetive: to evaluate the effect of LH surge and progesterone rise in IUI cycles under gonadotropin stimulation with GnRH antagonist coadministration on pregnancy rates (PR). Study Design: The population under study consisted of 152 women prospectively studied and subjected to IUI. Results The higher the progesterone cutoff value, the lower the PR were 26.5% and 10.9% when the cutoff was 1 ng/mL, 26.0% and 8.6% when the cutoff was 1.2 ng/mL, 25.6% and 7.1% when the cutoff was 1.4 ng/mL and 25.3% and 0% when the cutoff was 1.6 ng/mL. Conclusion: In IUI cycles under GnRH antagonist coadministration, serum progesterone levels over 1.0 ng/mL are associated with lower PR, the higher the progesterone levels, the lower the PR.

引用

页码：157 / 161

页数：5

共 28 条

[1] GnRH antagonist-induced inhibition of the premature LH surge increases pregnancy rates in IUI-stimulated cycles. A prospective randomized trial [J].