Klebsiella pneumoniae ST258 Producing KPC-3 Identified in Italy Carries Novel Plasmids and OmpK36/OmpK35 Porin Variants

被引：150

作者：

Garcia-Fernandez, Aurora ^{[1
]}

Villa, Laura ^{[1
]}

Carta, Claudio ^{[2
]}

Venditti, Carolina ^{[1
]}

Giordano, Alessandra ^{[3
]}

Venditti, Mario ^{[3
]}

Mancini, Carlo ^{[3
]}

Carattoli, Alessandra ^{[1
]}

机构：

[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy

[2] Ist Super Sanita, Dept Haematol Oncol & Mol Med, I-00161 Rome, Italy

[3] Univ Roma La Sapienza, Dept Publ Hlth & Infect Dis, Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 04期

关键词：

SPECTRUM-BETA-LACTAMASE; SEQUENCE TYPE 258; CARBAPENEMASE; RESISTANCE; EMERGENCE; GENES;

D O I：

10.1128/AAC.05308-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A carbapenemase-resistant Klebsiella pneumoniae strain, clone ST258 producing KPC-3, was fully characterized. The entire plasmid content was investigated, thereby identifying plasmids of the IncFII(k) (two of them similar to pKPQIL and pKPN3, respectively), IncX, and COlE types, carrying a formidable set of resistance genes against toxic compounds, metals, and antimicrobial drugs and a novel iron(III) uptake system.

引用

页码：2143 / 2145

页数：3

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