Sclerotiamide: A new member of the paraherquamide class with potent antiinsectan activity from the sclerotia of Aspergillus sclerotiorum

被引：105

作者：

Whyte, AC

Gloer, JB

Wicklow, DT

Dowd, PF

机构：

[1] UNIV IOWA, DEPT CHEM, IOWA CITY, IA 52242 USA

[2] USDA ARS, NATL CTR AGR UTILIZAT RES, PEORIA, IL 61604 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 11期

关键词：

D O I：

10.1021/np960607m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Sclerotiamide (1), a new fungal natural product related to the paraherquamides, was isolated by bioassay-guided fractionation of antiinsectan organic extracts from the sclerotia of Aspergillus sclerotiorum (NRRL 5167). The structure was determined primarily through H-1-NMR, C-13-NMR, HMQC, and HMBC experiments. Sclerotiamide causes significant mortality and unusual physiological effects in dietary assays against the corn earworm Helicoverpa zea.

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页码：1093 / 1095

页数：3

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