Desmosine, a biomarker for COPD: old and in the way

被引：11
作者：
Luisetti, M. [1 ]
Stolk, J. [3 ]
Iadarola, P. [2 ]
机构：
[1] Univ Pavia, Fdn IRCCS San Matteo Hosp, Dept Mol Med, Sect Pneumol, I-27100 Pavia, Italy
[2] Univ Pavia, Fdn IRCCS San Matteo Hosp, Dept Biochem, I-27100 Pavia, Italy
[3] Leiden Univ, Med Ctr, Dept Pulmonol, Leiden, Netherlands
来源：
EUROPEAN RESPIRATORY JOURNAL | 2012年 / 39卷 / 04期
关键词：
OBSTRUCTIVE PULMONARY-DISEASE; SURROGATE END-POINTS; ELASTIN DEGRADATION; ISODESMOSINE; TRIALS;
D O I：
10.1183/09031936.00172911
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页码：797 / 798
页数：2
相关论文
共 17 条
  • [1] Pulmonary biomarkers in chronic obstructive pulmonary disease
    Barnes, Peter J.
    Chowdhury, Badrul
    Kharitonov, Sergei A.
    Magnussen, Helgo
    Page, Clive P.
    Postma, Dirkje
    Saetta, Marina
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (01) : 6 - 14
  • [2] The fibrinogen cleavage product Aα-Val360, a specific marker of neutrophil elastase activity in vivo
    Carter, Richard I.
    Mumford, Richard A.
    Treonze, Kelly M.
    Finke, Paul E.
    Davies, Phillip
    Si, Qian
    Humes, John L.
    Dirksen, Asger
    Piitulainen, Eeva
    Ahmad, Ali
    Stockley, Robert A.
    [J]. THORAX, 2011, 66 (08) : 686 - 691
  • [3] Outcomes for COPD pharmacological trials:: from lung function to biomarkers
    Cazzola, M.
    MacNee, W.
    Martinez, F. J.
    Rabe, K. F.
    Franciosi, L. G.
    Barnes, P. J.
    Brusasco, V.
    Burge, P. S.
    Calverley, P. M. A.
    Celli, B. R.
    Jones, P. W.
    Mahler, D. A.
    Make, B.
    Miravitlles, M.
    Page, C. P.
    Palange, P.
    Parr, D.
    Pistolesi, M.
    Rennard, S. I.
    Moelken, M. P. Rutten-Van
    Stockley, R.
    Sullivan, S. D.
    Wedzicha, J. A.
    Wouters, E. F.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2008, 31 (02) : 416 - 468
  • [4] Considerations in the evaluation of surrogate endpoints in clinical trials: Summary of a National Institutes of Health Workshop
    De Gruttola, VG
    Clax, P
    DeMets, DL
    Downing, GJ
    Ellenberg, SS
    Friedman, L
    Gail, MH
    Prentice, R
    Wittes, J
    Zeger, SL
    [J]. CONTROLLED CLINICAL TRIALS, 2001, 22 (05): : 485 - 502
  • [5] THE REGULATION OF LUNG ELASTIN SYNTHESIS
    FOSTER, JA
    CURTISS, SW
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 259 (02): : L13 - L23
  • [6] Long-term Variability of Desmosine/Isodesmosine as Biomarker in Alpha-1-antritrypsin Deficiency-related COPD
    Fregonese, Laura
    Ferrari, Fabio
    Fumagalli, Marco
    Luisetti, Maurizio
    Stolk, Jan
    Iadarola, Paolo
    [J]. COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2011, 8 (05) : 329 - 333
  • [7] Contribution of emphysema and small airways in COPD
    Gelb, AF
    Hogg, JC
    Muller, NL
    Schein, MJ
    Kuei, J
    Tashkin, DP
    Epstein, JD
    Kollin, J
    Green, RH
    Zamel, N
    Elliott, WM
    Hadjiaghai, L
    [J]. CHEST, 1996, 109 (02) : 353 - 359
  • [8] Total desmosines in plasma and urine correlate with lung function
    Lindberg, C. A.
    Engstrom, G.
    de Verdier, M. Gerhardsson
    Nihlen, U.
    Anderson, M.
    Forsman-Semb, K.
    Svartengren, M.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2012, 39 (04) : 839 - 845
  • [9] Desmosine as a biomarker of elastin degradation in COPD: current status and future directions
    Luisetti, M.
    Ma, S.
    Iadarola, P.
    Stone, P. J.
    Viglio, S.
    Casado, B.
    Lin, Y. Y.
    Snider, G. L.
    Turino, G. M.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2008, 32 (05) : 1146 - 1157
  • [10] Measurements of desmosine and isodesmosine by mass spectrometry in COPD
    Ma, Shuren
    Lin, Yong Y.
    Turino, Gerard M.
    [J]. CHEST, 2007, 131 (05) : 1363 - 1371
12