High Frequency of GATA2 Mutations in Cytogenetically Normal Acute Myeloid Leukemia with Biallelic CEBPA Mutations Identified by Exome Sequencing

被引:3
|
作者
Dufour, Annika [1 ]
Konstandin, Nikola [1 ]
Ksienzyk, Bianka [1 ]
Zellmeier, Evelyn [1 ]
Benthaus, Tobias [1 ]
Yaghmaie, Marjan [3 ]
Graf, Alexander [2 ]
Krebs, Stefan [2 ]
Hauser, Andreas [2 ]
Blum, Helmut [2 ]
Kakadia, Purvi [1 ]
Schneider, Stephanie [1 ]
Braess, Jan [4 ]
Woermann, Bernhard Josef [5 ]
Berdel, Wolfgang E. [6 ]
Buechner, Thomas [6 ]
Hiddemann, Wolfgang [1 ]
Spiekermann, Karsten [1 ]
Bohlander, Stefan K. [1 ]
Greif, Philipp A. [1 ]
机构
[1] Dept Med, Munich, Germany
[2] Ludwig Maximilians Univ LMU Munich, Gene Ctr, Munich, Germany
[3] Univ Tehran Med Sci, BMT Res Ctr, Tehran, Iran
[4] Krankenhaus Barmherzigen Bruder, Regensburg, Germany
[5] NA, Hamburg, Germany
[6] Univ Munster, Dept Med Hematol Oncol & Pneumol A, Munster, Germany
关键词
D O I
10.1182/blood.V118.21.72.72
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:35 / 35
页数:1
相关论文
共 50 条
  • [41] Acute Myeloid Leukemia Characterized by Four CEBPA Mutations
    Beckman, Amy
    Meredith, Matthew
    Rangan, Aruna
    Thyagarajan, Bharat
    Yohe, Sophia
    Mroz, Pawel
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2018, 150 : S103 - S104
  • [42] Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations
    Yuan, Ji
    He, Rong
    Alkhateeb, Hassan B.
    CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2023, 18 (05) : 121 - 129
  • [43] Haplotype Phase of CEBPA Mutations in Acute Myeloid Leukemia
    Harley, S.
    Mroz, P.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2020, 22 (11): : S24 - S25
  • [44] Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations
    Ji Yuan
    Rong He
    Hassan B. Alkhateeb
    Current Hematologic Malignancy Reports, 2023, 18 : 121 - 129
  • [45] Differential prognosis impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia
    Boissel, Nicolas
    Nibourel, Olivier
    Renneville, Aline
    Huchette, Pascal
    Dombret, Herve
    Preudhomme, Claude
    BLOOD, 2011, 117 (13) : 3696 - 3697
  • [46] A simple cytofluorimetric score may optimize testing for biallelic CEBPA mutations in patients with acute myeloid leukemia
    Marcolin, Riccardo
    Guolo, Fabio
    Minetto, Paola
    Clavio, Marino
    Manconi, Lorenzo
    Ballerini, Filippo
    Carli, Alessandro
    Passannante, Monica
    Colombo, Nicoletta
    Carminati, Enrico
    Pugliese, Girolamo
    Tedone, Elisabetta
    Contini, Paola
    Mangerini, Rosa
    Kunkl, Annalisa
    Miglino, Maurizio
    Cagnetta, Antonia
    Cea, Michele
    Gobbi, Marco
    Lemoli, Roberto Massimo
    LEUKEMIA RESEARCH, 2019, 86
  • [47] Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
    Ostergaard, Pia
    Simpson, Michael A.
    Connell, Fiona C.
    Steward, Colin G.
    Brice, Glen
    Woollard, Wesley J.
    Dafou, Dimitra
    Kilo, Tatjana
    Smithson, Sarah
    Lunt, Peter
    Murday, Victoria A.
    Hodgson, Shirley
    Keenan, Russell
    Pilz, Daniela T.
    Martinez-Corral, Ines
    Makinen, Taija
    Mortimer, Peter S.
    Jeffery, Steve
    Trembath, Richard C.
    Mansour, Sahar
    NATURE GENETICS, 2011, 43 (10) : 929 - 931
  • [48] A SIMPLE CYTOFLUORIMETRIC SCORE MAY OPTIMIZE TESTING FOR BIALLELIC CEBPA MUTATIONS IN PATIENTS WITH ACUTE MYELOID LEUKEMIA
    Marcolin, R.
    Guolo, F.
    Minetto, P.
    Clavio, M.
    Ballerini, F.
    Manconi, L.
    Carli, A.
    Passannante, M.
    Todiere, A.
    Colombo, N.
    Carminati, E.
    Pugliese, G.
    Tedone, E.
    Contini, P.
    Mangerini, R.
    Kunkl, A.
    Miglino, M.
    Cagnetta, A.
    Cea, M.
    Gobbi, M.
    Lemoli, R. M.
    HAEMATOLOGICA, 2019, 104 : 137 - 137
  • [49] Favorable prognosis of biallelic CEBPA gene mutations in acute myeloid leukemia patients: a meta-analysis
    Li, Hong-Ying
    Deng, Dong-Hong
    Huang, Ying
    Ye, Fang-Hui
    Huang, Lu-Lu
    Xiao, Qiang
    Zhang, Bing
    Ye, Bing-Bing
    Lai, Yong-Rong
    Mo, Zeng-Nan
    Liu, Zhen-Fang
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2015, 94 (05) : 439 - 448
  • [50] Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA)
    Brown, Anna L.
    Hahn, Christopher N.
    Scott, Hamish S.
    BLOOD, 2020, 136 (01) : 24 - 35