Acute Respiratory Distress Syndrome 2022 2 Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

被引:205
作者
Gorman, Ellen A. [1 ]
O'Kane, Cecilia M. [1 ]
McAuley, Daniel F. [1 ,2 ]
机构
[1] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast, North Ireland
[2] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast BT9 7BL, North Ireland
关键词
EXTRACORPOREAL MEMBRANE-OXYGENATION; HIGH-FREQUENCY OSCILLATION; END-EXPIRATORY PRESSURE; FLOW NASAL OXYGEN; ACUTE LUNG INJURY; BERLIN DEFINITION; CLINICAL-TRIAL; CRITICAL-CARE; DOUBLE-BLIND; ARDS;
D O I
10.1016/S0140-6736(22)01439-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by cardiac failure or fluid overload. ARDS is defined by the Berlin criteria. In this Series paper the diagnosis, management, outcomes, and long-term sequelae of ARDS are reviewed. Potential limitations of the ARDS definition and evidence that could inform future revisions are considered. Guideline recommendations, evidence, and uncertainties in relation to ARDS management are discussed. The future of ARDS strives towards a precision medicine approach, and the framework of treatable traits in ARDS diagnosis and management is explored.
引用
收藏
页码:1157 / 1170
页数:14
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