Susceptibility to caspofungin of Candida spp. strains isolated in Ceara, Northeastern Brazil

被引：0
|
作者：
Rocha da Silva, C. [1 ,2 ]
de Sousa Campos, R. [1 ,2 ]
Adalgiza dos Santos Neta, M. [1 ,2 ]
Rozelle Ferreira Angelo, M. [3 ]
Iury Ferreira Magalhaes, H. [1 ,4 ]
Coelho Cavalcanti, B. [4 ]
de Moraes, M. Odorico [4 ]
Silveira Macedo, D. [4 ]
Vitoriano Nobre Junior, H. [1 ,2 ,4 ]
机构：
[1] Univ Fed Ceara, Lab Bioprospect & Expt Yeast LABEL, Dept Clin & Toxicol Anal, Sch Pharm, Fortaleza, Ceara, Brazil
[2] Univ Fed Ceara, Sch Med, Mycol Ctr, Dept Pathol & Legal Med, Fortaleza, Ceara, Brazil
[3] Cent Publ Hlth Lab LACEN CE, Fortaleza, Ceara, Brazil
[4] Univ Fed Ceara, Dept Physiol & Pharmacol, Fortaleza, Ceara, Brazil
来源：
JOURNAL DE MYCOLOGIE MEDICALE | 2011年 / 21卷 / 04期
关键词：
Caspofungin; Candida spp; Microdilution; Susceptibility tests; ORTHOPSILOSIS; METAPSILOSIS; PARAPSILOSIS; PROPOSAL;
D O I：
10.1016/j.mycmed.2011.09.006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Caspofungin is an echinocandin prescribed for the treatment of invasive fungal infections caused by Candida spp. and Aspergillus spp. The aim of this study is to assess the degree of susceptibility of Candida spp., isolated from blood cultures in the state of Ceara (Brazil) to caspofungin by the broth microditution method. Thirty-three strains of Candida spp. were selected for the test (seven C. olbicans, nine C. tropicalis and 17 C. parapsilosis); these strains are the most commonly isolates of fungal infections in Ceara. The results of susceptibility tests by broth microdilution can be read at 24 or 48 hours after testing, without compromising test interpretations. C. parapsilosis exhibited the highest MICs when compared with the MICs of caspofungin against C. albicans and C. tropicalis. (C) 2011 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：273 / 276
页数：4
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