Does intravenous administration of human albumin prevent severe ovarian hyperstimulation syndrome?

被引:22
作者
Lewit, N
Kol, S
Ronen, N
ItskovitzEldor, J
机构
[1] TECHNION ISRAEL INST TECHNOL,RAMBAM MED CTR,DEPT OBSTET & GYNECOL,IL-31096 HAIFA,ISRAEL
[2] TECHNION ISRAEL INST TECHNOL,FAC MED,IL-31096 HAIFA,ISRAEL
关键词
human albumin; ovarian hyperstimulation syndrome; IVF; ovulation induction; high risk subjects;
D O I
10.1016/S0015-0282(16)58584-7
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To report our experience with IV albumin as a means to prevent ovarian hyperstimulation syndrome (OHSS) in high-risk patients. Design: Retrospective case-series. Setting: University hospital-based IVF program. Patients: Five women undergoing controlled ovarian stimulation for IVF. Based on previous history and/or E(2) measurements and number of ovarian follicles, these patients were considered to be at high risk for developing OHSS. Interventions: Intravenous albumin was given at the time of oocyte retrieval, Additional doses were given 12 and 24 hours later. Main Outcome Measure: Development of OHSS. Results: Four patients developed OHSS; two of them had the severe form of the syndrome. Conclusions: Severe OHSS may develop in high-risk patients despite the prophylactic administration of IV albumin.
引用
收藏
页码:654 / 656
页数:3
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