Matrix metalloproteinases and the development of cancer

被引：476
作者：
Coussens, LM
Werb, Z
机构：
[1] UNIV CALIF SAN FRANCISCO,HORMONE RES INST,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT ANAT,SAN FRANCISCO,CA 94143
来源：
CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 11期
关键词：
D O I：
10.1016/S1074-5521(96)90178-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multistage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.
引用
收藏
页码：895 / 904
页数：10
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