Alcohol use disorder and the gut

被引：26
|
作者：
Haber, Paul S. [1 ,2 ]
Kortt, Nicholas C. [1 ]
机构：
[1] Royal Prince Alfred Hosp, Camperdown, NSW 2050, Australia
[2] Univ Sydney, Sydney, NSW 2050, Australia
来源：
ADDICTION | 2021年 / 116卷 / 03期
关键词：
Alcohol; cancer; gastrointestinal tract; gastro-oesophageal reflux; pancreatitis; pathogenesis; DOSE-RESPONSE METAANALYSIS; SEVERE ACUTE-PANCREATITIS; HELICOBACTER-PYLORI INFECTION; COLORECTAL-CANCER RISK; PEPTIC-ULCER DISEASE; LIVER-DISEASE; ANTIOXIDANT THERAPY; ENTERAL NUTRITION; PERITONEAL-LAVAGE; SMALL-INTESTINE;
D O I：
10.1111/add.15147
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Acute and chronic gastrointestinal problems are common in the setting of excessive alcohol use, and excessive alcohol use is associated with injury to all parts of the gastrointestinal tract. There is mounting evidence of gastrointestinal injury and increased cancer risk even from moderate alcohol consumption. The major causes of alcohol-related morbidity and mortality within the gastrointestinal system are liver disease, pancreatitis and gastrointestinal cancer. Other alcohol-related intestinal dysfunction is common but not life-threatening, leading to diarrhoea, malabsorption and nutritional deficiencies. This review describes non-neoplastic and neoplastic alcohol-related disorders of the gastrointestinal tract, omitting the liver, which has been reviewed elsewhere.
引用
收藏
页码：658 / 667
页数：10
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