Solvothermal synthesis and modification of NaYF4:Yb/Er@NaLuF4:Yb for enhanced up-conversion luminescence for bioimaging

被引：12
作者：
Li, Hua [1 ]
Liu, Xuguang [1 ]
Li, Xia [1 ]
机构：
[1] Qingdao Univ Sci & Technol, Coll Mat Sci & Engn, Qingdao 266042, Peoples R China
来源：
RSC ADVANCES | 2019年 / 9卷 / 72期
基金：
中国国家自然科学基金;
关键词：
CORE-SHELL; NANOPARTICLES; PHASE; NANOCRYSTALS; NAYF4-YB; ER; ER3+; SIZE; FLUORESCENCE; EMISSION; STRATEGY;
D O I：
10.1039/c9ra08921g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Water-soluble NaYF4:Yb/Er@NaLuF4:Yb up-converting nanoparticles (UCNPs) with a strong green emission were successfully prepared by a solvothermal method in a short period of time and at a low temperature. First, the hydrophobic UCNPs were prepared by a simple solvothermal method, then modified using a polyetherimide (PEI) surfactant or oxidation of the oleic acid ligands with the Lemieux-von Rudloff reagent. The modified UCNPs, having an average particle diameter of 60 +/- 5 nm, showed a high dispersity. The oleic acid ligand on the sample surface was oxidized azelaic acid (HOOC(CH2)(7)COOH), identified from Fourier transform infrared (FTIR) spectroscopy, which results in the generation of free carboxylic acid, hence conferring a high solubility in water. The 3-4,5-dimethylthiazol-2-yl-2,5-diphenyl tetrazolium bromide (MTT) method and cell-targeted labeling proved that oleic acid-capped UCNPs after oxidation (UCNPs-OAO) have a higher biocompatibility than polyetherimide-capped UCNPs (UCNPs-PEI). Therefore, the UCNPs-OAO have a great potential in biomedical applications, such as multimodal imaging, targeted therapy, and gene therapy.
引用
收藏
页码：42163 / 42171
页数：9
相关论文
共 53 条
[21]   Crystal transition control of NaYE4 upconversion microcrystals through addition of Na2HPO4 [J].
Lv, Meng ;
Li, Xia .
MATERIALS & DESIGN, 2015, 88 :514-519
[22]   A Yolk-like Multifunctional Platform for Multimodal Imaging and Synergistic Therapy Triggered by a Single Near-Infrared Light [J].
Lv, Ruichan ;
Yang, Piaoping ;
He, Fei ;
Gai, Shili ;
Li, Chunxia ;
Dai, Yunlu ;
Yang, Guixin ;
Lin, Jun .
ACS NANO, 2015, 9 (02) :1630-1647
[23]   Size- and phase-controlled synthesis of monodisperse NaYF4:Yb,Er nanocrystals from a unique delayed nucleation pathway monitored with upconversion spectroscopy [J].
Mai, Hao-Xin ;
Zhang, Ya-Wen ;
Sun, Ling-Dong ;
Yan, Chun-Hua .
JOURNAL OF PHYSICAL CHEMISTRY C, 2007, 111 (37) :13730-13739
[24]   High-quality sodium rare-earth fluoride nanocrystals: Controlled synthesis and optical properties [J].
Mai, Hao-Xin ;
Zhang, Ya-Wen ;
Si, Rui ;
Yan, Zheng-Guang ;
Sun, Ling-Dong ;
You, Li-Ping ;
Yan, Chun-Hua .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (19) :6426-6436
[25]   Targeting Hepatic Cancer Cells with PEGylated Dendrimers Displaying N-Acetylgalactosamine and SP94 Peptide Ligands [J].
Medina, Scott H. ;
Tiruchinapally, Gopinath ;
Chevliakov, Maxim V. ;
Durmaz, Yasemin Yuksel ;
Stender, Rachell N. ;
Ensminger, William D. ;
Shewach, Donna S. ;
ElSayed, Mohamed E. H. .
ADVANCED HEALTHCARE MATERIALS, 2013, 2 (10) :1337-1350
[26]   The influence of thermal effect induced by Yb3+ sensitization on color regulation in Gd2O3:Yb3+, Er3+ upconversion phosphors [J].
Pang, Tao ;
Lu, Wen-hui .
CERAMICS INTERNATIONAL, 2017, 43 (01) :1061-1065
[27]   PEG-capped, lanthanide doped GdF3 nanoparticles: luminescent and T2 contrast agents for optical and MRI multimodal imaging [J].
Passuello, Tiziana ;
Pedroni, Marco ;
Piccinelli, Fabio ;
Polizzi, Stefano ;
Marzola, Pasquina ;
Tambalo, Stefano ;
Conti, Giamaica ;
Benati, Donatella ;
Vetrone, Fiorenzo ;
Bettinelli, Marco ;
Speghini, Adolfo .
NANOSCALE, 2012, 4 (24) :7682-7689
[28]   Upconversion core/shell nanoparticles with lowered surface quenching for fluorescence detection of Hg2+ ions [J].
Shi, Lichun ;
Hu, Junshan ;
Wu, Xiaofeng ;
Zhan, Shiping ;
Hu, Shigang ;
Tang, Zhijun ;
Chen, Mingshu ;
Liu, Yunxin .
DALTON TRANSACTIONS, 2018, 47 (46) :16445-16452
[29]   The Effect of Surface Coating on Energy Migration-Mediated Upconversion [J].
Su, Qianqian ;
Han, Sanyang ;
Xie, Xiaoji ;
Zhu, Haomiao ;
Chen, Hongyu ;
Chen, Chih-Kai ;
Liu, Ru-Shi ;
Chen, Xueyuan ;
Wang, Feng ;
Liu, Xiaogang .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (51) :20849-20857
[30]   Substituted hydroxyapatites for biomedical applications: A review [J].
Supova, Monika .
CERAMICS INTERNATIONAL, 2015, 41 (08) :9203-9231
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