HBV vaccine and dermatomyositis: is there an association?

被引：35

作者：

Altman, Arie ^{[3
,4
]}

Szyper-Kravitz, Martine ^{[3
,4
]}

Shoenfeld, Yehuda ^{[1
,2
,3
,4
]}

机构：

[1] Chaim Sheba Med Ctr, Dept Med B, IL-52621 Tel Hashomer, Israel

[2] Tel Aviv Univ, Chair Autoimmune Dis, IL-69978 Tel Aviv, Israel

[3] Tel Aviv Univ, Sackler Fac Med, Dept Med B, IL-69978 Tel Aviv, Israel

[4] Tel Aviv Univ, Sackler Fac Med, Ctr Autoimmune Dis, IL-69978 Tel Aviv, Israel

来源：

RHEUMATOLOGY INTERNATIONAL | 2008年 / 28卷 / 06期

关键词：

hepatitis virus; HBV vaccine; dermatomyositis; autoimmunity; vaccine;

D O I：

10.1007/s00296-007-0485-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The etiology of dermatomyositis is unknown, but immune mechanisms play an important role. Several dermatological manifestations have been reported among carriers of hepatitis B surface antigen, and after vaccination with the HBV vaccine. Almost all the skin reactions described were peculiar skin eruptions suggestive of an immune complex reaction. Some authors described the occurrence of dermatomyositis after BCG and influenza vaccination. We report a case of a 6-year-old child, who was vaccinated for hepatitis B virus and developed a flu-like disease accompanied by a skin rash, which had the typical features of dermatomyositis. The association of vaccination with autoimmunity is discussed.

引用

页码：609 / 612

页数：4

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