Differential diagnosis of posterior fossa tumours in children: new insights

被引:32
作者
D'Arco, Felice [1 ]
Khan, Faraan [1 ]
Mankad, Kshitij [1 ]
Ganau, Mario [2 ]
Caro-Dominguez, Pablo [3 ]
Bisdas, Sotirios [4 ]
机构
[1] Great Ormond St Hosp NHS Trust, Dept Radiol, Unit Paediat Neuroradiol, Great Ormond St, London WC1N 3JH, England
[2] Univ Toronto, Toronto Western Hosp, Dept Neurosurg, Toronto, ON, Canada
[3] Hosp VIAMED, Dept Diagnost Imaging, Seville, Spain
[4] Natl Hosp Neurol & Neurosurg, Lysholm Dept Neuroradiol, London, England
关键词
Brain; Children; Magnetic resonance imaging; Neoplasm; Posterior fossa; IMAGING CHARACTERISTICS; MOLECULAR SUBGROUPS; MEDULLOBLASTOMA; CLASSIFICATION; MRI; EPENDYMOMAS;
D O I
10.1007/s00247-018-4224-7
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Central nervous system neoplasms are the most common solid tumours that develop in children, with the greatest proportion located in the infratentorium. The 2016 World Health Organization Central Nervous System tumour classification evolved from the 2007 edition with the integration of molecular and genetic profiling into the diagnosis, the addition of new entities and the removal of others. Radiology can assist with the subtyping of tumours from certain characteristics described below to provide prognostic information and guide further management. The latest insights into the radiologic characteristics of these posterior fossa tumours are presented below: medulloblastoma, ependymoma, pilocytic astrocytoma, embryonal tumours with multilayered rosettes, atypical teratoid rhabdoid tumours, diffuse midline glioma and the new entity of diffuse leptomeningeal glioneuronal tumours.
引用
收藏
页码:1955 / 1963
页数:9
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