Current status and future challenges for molecular imaging

被引:22
作者
Anderson, Carolyn J. [1 ,2 ,3 ,4 ]
Lewis, Jason S. [5 ,6 ,7 ]
机构
[1] Univ Pittsburgh, Dept Med, Pittsburgh, PA 15219 USA
[2] Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15219 USA
[3] Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA 15219 USA
[4] Univ Pittsburgh, Dept Pharmacol & Chem Biol, Pittsburgh, PA 15219 USA
[5] Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10021 USA
[6] Mem Sloan Kettering Canc Ctr, Program Mol Pharmacol, 1275 York Ave, New York, NY 10021 USA
[7] Weill Cornell Med Coll, New York, NY 10065 USA
来源
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES | 2017年 / 375卷 / 2107期
关键词
molecular imaging; radiochemistry; positron emission tomography; POSITRON-EMISSION-TOMOGRAPHY; SYSTEMIC INFLAMMATION; F-18-FLUOROESTRADIOL PET; INTRATUMOR HETEROGENEITY; IN-VIVO; PHASE-I; CANCER; IMMUNOTHERAPY; RADIOGENOMICS; RADIOMICS;
D O I
10.1098/rsta.2017.0023
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Molecular imaging (MI), used in its wider sense of biology at the molecular level, is a field that lies at the intersection of molecular biology and traditional medical imaging. As advances in medicine have exponentially expanded over the last few decades, so has our need to better understand the fundamental behaviour of living organisms in a non-invasive and timely manner. This commentary draws from topics the authors addressed in their presentations at the 2017 Royal Society Meeting 'Challenges for chemistry in molecular imaging', as well as a discussion of where MI is today and where it is heading in the future. This article is part of the themed issue 'Challenges for chemistry in molecular imaging'.
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页数:11
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