Withanolides from the flowers of Datura fastuosa

被引:11
作者
Manickam, M [1 ]
Srivastava, A [1 ]
Ray, AB [1 ]
机构
[1] Banaras Hindu Univ, Inst Med Sci, Dept Med Chem, Varanasi 221005, Uttar Pradesh, India
关键词
Datura fastuosa Linn; Solanaceae; withanolides; withafastuosin F; withametelin; withametelin B; withatatulin B; withatatulin D; withafastuosin E;
D O I
10.1016/S0031-9422(97)00718-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Withafastuosin F, a new pentahydroxy withanolide and several other known withanolides have been isolated from the flowers of Datura fastuosa. The structure of the new compound has been elucidated as 5 alpha,6 beta,12 beta,21,27-penthahydroxy-1-oxo-witha-2,24-dienol from comprehensive spectral analysis. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1427 / 1429
页数:3
相关论文
共 11 条
[1]  
CHANDHOKE N, 1978, INDIAN J EXP BIOL, V16, P648
[2]  
CHANDHOKE N, 1978, INDIAN J EXP BIOL, V16, P419
[3]   WITHANOLIDES .21. ADDITIONAL WITHANOLIDES OF DATURA-METEL [J].
GUPTA, M ;
BAGCHI, A ;
RAY, AB .
JOURNAL OF NATURAL PRODUCTS, 1991, 54 (02) :599-602
[4]  
MANICKAM M, 1994, J CHEM RES-S, P306
[5]   WITHANOLIDES OF DATURA-FASTUOSA LEAVES [J].
MANICKAM, M ;
SINHABAGCHI, A ;
SINHA, SC ;
GUPTA, M ;
RAY, AB .
PHYTOCHEMISTRY, 1993, 34 (03) :868-870
[6]  
Manickam M, 1997, PHYTOTHER RES, V11, P384, DOI 10.1002/(SICI)1099-1573(199708)11:5<384::AID-PTR105>3.3.CO
[7]  
2-J
[8]  
Manickam M, 1996, INDIAN J CHEM B, V35, P1311
[9]   TOHOKU UNIVERSITY SERIES ON STEROIDS .35. WITHAMETELIN, A HEXACYCLIC WITHANOLIDE OF DATURA-METEL [J].
OSHIMA, Y ;
BAGCHI, A ;
HIKINO, H ;
SINHA, SC ;
SAHAI, M ;
RAY, AB .
TETRAHEDRON LETTERS, 1987, 28 (18) :2025-2028
[10]  
Ray A B, 1994, Fortschr Chem Org Naturst, V63, P1