N-Heterocyclic Carbene Palladium(II) Amine Complexes: The Role of Primary Aryl- or Alkylamine Binding and Applications in the Buchwald-Hartwig Amination Reaction

被引：8

作者：

Hsu, Yu-Cheng ^{[1
,2
]}

Chen, Ming-Tsz ^{[1
,2
]}

机构：

[1] Providence Univ, Dept Appl Chem, Taichung 43301, Taiwan

[2] 200,Sec 7,Taiwan Blvd, Taichung 43301, Taiwan

来源：

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY | 2022年 / 2022卷 / 01期

关键词：

Arylamines; Alkylamines; Buchwald-Hartwig amination reaction; Homogeneous catalysis; Palladium; ORTHO-SUBSTITUTED BIARYLS; SUZUKI-MIYAURA; CATALYTIC-ACTIVITY; COUPLING REACTIONS; C-N; NHC; CHLORIDES; PRECATALYSTS; ACTIVATION; LIGANDS;

D O I：

10.1002/ejic.202100828

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

N-heterocyclic carbene-palladium(II) amine complexes bearing primary aryl- or alkylamines were synthesized. The prepared complexes were characterized by single crystal X-ray diffraction as well as NMR spectroscopy. These complexes exhibited good catalytic activities for the Buchwald-Hartwig amination reaction of aryl chlorides to afford arylated anilines under mild conditions. All reactions were carried out in air and all starting materials were used as supplied without purification. 21 expected coupling products were obtained in moderate to high yields under optimum conditions.

引用

页数：9