Attachment of cells to poly(styrene-co-acrylic acid) thin films with various charge densities

被引：10
|
作者：
Jung, Hyosook
Kwak, Byeongdo
Yang, Ho Sung
Tae, Giyoong
Kim, Joon-Seop
Shin, Kwanwoo [1 ]
机构：
[1] Sogang Univ, Dept Chem & Interdisciplinary Program Integrated, Seoul 121742, South Korea
[2] Gwangju Inst Sci & Technol, Dept Mat Sci & Engn, Kwangju 500712, South Korea
[3] Chosun Univ, Dept Polymer Sci & Engn, Educ Ctr Technol Adv Mat & Parts BK21, Kwangju 501600, South Korea
来源：
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2008年 / 313卷 / 562-566期
关键词：
polyelectrolytes; cell adhesion; cell attachment; charge density;
D O I：
10.1016/j.colsurfa.2007.05.070
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Adsorption and growth behaviors of fibroblast cells have been studied on poly(styrene-ran-acrylic acid) (PS-y-AA) films with four different degrees of charge contents (y = 0%, 5.6%, 10.0%, and 15.3%) and tissue culture polystyrene (TCPS). The structures and adsorption behavior of fibroblast cells were found to be quite different as a function of charge density. As the degree of charge density of PS-y-AA is increased, more cell adhesion and proliferation were observed. However, there was no significant difference in the adsorption of fibroblast cells in the absence of serum, indicating that serum proteins may play a critical role in the adhesion of cells to carboxylic acid groups. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：562 / 566
页数：5
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