Lipid Profiling, Particle Size Determination, and in Vitro Simulated Gastrointestinal Lipolysis of Mature Human Milk and Infant Formula

被引：46

作者：

Cheong, Ling-Zhi ^{[1
]}

Jiang, Chenyu ^{[1
]}

He, Xiaoqian ^{[1
]}

Song, Shuang ^{[2
]}

Lai, Oi-Ming ^{[3
,4
]}

机构：

[1] Ningbo Univ, Coll Food & Pharmaceut Sci, Dept Food Sci & Engn, Ningbo 315211, Zhejiang, Peoples R China

[2] Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing 100050, Peoples R China

[3] Univ Putra Malaysia, Fac Biotechnol & Bimolecular Sci, Dept Bioproc Technol, Upm Serdang 43400, Selangor, Malaysia

[4] Univ Putra Malaysia, Inst Biosci, Upm Serdang 43400, Selangor, Malaysia

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2018年 / 66卷 / 45期

基金：

中国国家自然科学基金;

关键词：

human milk; infant formulas; in vitro gastrointestinal lipolysis; lipid profiling; particle size; POLYUNSATURATED FATTY-ACIDS; BREAST-MILK; PHYSICOCHEMICAL PROPERTIES; DIGESTION; MEMBRANE; GLOBULES; MODELS; SUPPLEMENTATION; PHOSPHOLIPIDS; HYDROLYSIS;

D O I：

10.1021/acs.jafc.8b03998

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Dairy technologists has attempted to produce "improved" infant formulas mimicking human milk by supplementation with bovine MFGM and/or phospholipids-enriched materials. The present study investigated and compared the lipid profile and particle sizes of mature human milk and infant formula fat globules (IF 1, IF 2, IF 3, and IF 4) and elucidated the relationship between physicochemical properties and in vitro simulated gastrointestinal lipolysis rate of the different milk samples. Despite having larger micron-sized fat globules, mature human milk demonstrated the highest gastrointestinal lipolysis rate with higher release of medium- and long-chain saturated fatty acids. In comparison, IF 3, which contained the lowest phospholipids content, demonstrated the lowest gastrointestinal lipolysis rate. Higher gastrointestinal lipolysis rate of mature human milk fat as compared to infant formula fats might be due to the presence of MFGM interfacial layer (phospholipids) surrounding the fat droplets which govern lipase activity on lipid droplets.

引用

页码：12042 / 12050

页数：9